Comparison of antigen immunoassay and reverse transcriptase assay for monitoring human immunodeficiency virus infection in an antiviral trial

Harold Burger, D. Paul, F. P. Siegal, I. Wendel, S. Neff, D. Eilbott, K. Gehan, R. Grimson, Barbara Weiser

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We compared the Abott enzyme immunoassay for human immunodeficiency virus (HIV) antigen with the reverse transcriptase assay (RTA) as a means of monitoring HIV infection during an antiviral trial. The Abbott enzyme immunoassay detected HIV earlier than RTA whether or not the patients were antigenemic and appears to be superior to RTA for detecting HIV in cultures used for monitoring clinical trials.

Original languageEnglish (US)
Pages (from-to)1890-1892
Number of pages3
JournalJournal of Clinical Microbiology
Volume26
Issue number9
StatePublished - 1988
Externally publishedYes

Fingerprint

RNA-Directed DNA Polymerase
Virus Diseases
Immunoassay
Antiviral Agents
HIV
Immunoenzyme Techniques
Antigens
HIV Reverse Transcriptase
Clinical Trials

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Comparison of antigen immunoassay and reverse transcriptase assay for monitoring human immunodeficiency virus infection in an antiviral trial. / Burger, Harold; Paul, D.; Siegal, F. P.; Wendel, I.; Neff, S.; Eilbott, D.; Gehan, K.; Grimson, R.; Weiser, Barbara.

In: Journal of Clinical Microbiology, Vol. 26, No. 9, 1988, p. 1890-1892.

Research output: Contribution to journalArticle

Burger, Harold ; Paul, D. ; Siegal, F. P. ; Wendel, I. ; Neff, S. ; Eilbott, D. ; Gehan, K. ; Grimson, R. ; Weiser, Barbara. / Comparison of antigen immunoassay and reverse transcriptase assay for monitoring human immunodeficiency virus infection in an antiviral trial. In: Journal of Clinical Microbiology. 1988 ; Vol. 26, No. 9. pp. 1890-1892.
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