Comparison of 2-Octylcyanoacrylate Versus 5-0 Fast-Absorbing Gut During Linear Wound Closures and the Effect on Wound Cosmesis

Anne R. Zhuang, Kourosh Beroukhim, April W Armstrong, Raja K. Sivamani, Daniel B. Eisen

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Although the use of 2-octylcyanoacrylate (OCA) in cutaneous surgery offers increased efficiency, there is scant data comparing scar outcomes achieved with OCA versus 5-0 fast-absorbing gut suture (FG). OBJECTIVE: To compare scar cosmesis achieved with OCA versus FG for surgical wound closure. MATERIALS AND METHODS: A total of 44 patients with postoperative defects of at least 3 cm were included. Half of each wound was randomized to receive closure with either OCA or FG. At 3 months, patients and 2 blinded observers evaluated each scar using the Patient and Observer Scar Assessment Scale (POSAS). RESULTS: The total observer POSAS score (mean [SD]) for the side repaired with OCA (12.3 [4.72]) and the side that received FG (11.6 [4.36]) did not differ significantly (p = .40). There was no significant difference in the total patient POSAS scores between closure with OCA (14.9 [8.67]) and FG (14.6 [8.90]) (p = .70). Based on observer POSAS scores, scar pigmentation was significantly worse on the scar half repaired with OCA (1.98 [0.91]) compared with FG (1.79 [0.80]) (p = .05). CONCLUSION: With the exception of inferior scar pigmentation with OCA, there was no statistically significant difference in wound cosmesis after linear wound closure with OCA versus FG.

Original languageEnglish (US)
Pages (from-to)628-634
Number of pages7
JournalDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Volume46
Issue number5
DOIs
StatePublished - May 1 2020

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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