Comparison of 18S and ITS-1 rDNA sequences of selected geographic isolates of Myxobolus cerebralis

Karl B. Andree, Mansour El-Matbouli, Rudolph W. Hoffman, Ronald Hedrick

Research output: Contribution to journalArticlepeer-review

61 Scopus citations


Myxobolus cerebralis, the myxosporean parasite-causing salmonid whirling disease, was first reported among rainbow trout (Oncorhynchus mykiss) in Germany in 1903. The parasite was reported for the first time in North America in 1958 among hatchery-reared trout in the eastern USA, presumably arriving with frozen trout shipments from Europe. A comparison of 18S and ITS-1 ribosomal DNA sequences was conducted to identify potential strain differences between selected geographic isolates of this parasite from Europe and North America. Only fourteen of 1700 base pairs were different in the 18S rRNA gene from isolates obtained from California and West Virginia in the USA, and the Federal German Republic. No evidence for strain differences was obtained from ITS-1 sequences that were found to be identical among all parasite isolates. This finding is consistent with the hypothesis that the parasite was recently introduced to the USA from Europe.

Original languageEnglish (US)
Pages (from-to)771-775
Number of pages5
JournalInternational Journal for Parasitology
Issue number5
StatePublished - May 1 1999


  • 18S
  • ITS-1
  • Myxobolus cerebralis
  • Ribosomal DNA
  • Salmonids
  • Whirling disease

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases


Dive into the research topics of 'Comparison of 18S and ITS-1 rDNA sequences of selected geographic isolates of Myxobolus cerebralis'. Together they form a unique fingerprint.

Cite this