Comparative pathology of mammary tumorigenesis in transgenic mice

Robert Cardiff, Robert J. Munn

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Mammary tumors arise in transgenic mice bearing growth factors, proto-oncogenes, oncogenes and tumor suppressor genes. The tumors arise from hyperplasias. The tumor natural history and histogenesis are oncogene specific. Interactions between oncogenes may impede or accelerate tumorigenesis.

Original languageEnglish (US)
Pages (from-to)13-19
Number of pages7
JournalCancer Letters
Volume90
Issue number1
DOIs
StatePublished - Mar 23 1995

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Keywords

  • Breast cancer
  • Histogenesis
  • Oncogene
  • Transgenic mice

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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