Abstract
The genomics era, spearheaded by dazzling technological developments in human and mouse gene mapping, has additionally provoked extensive comparative gene mapping projects for domestic species of several vertebrate orders. As the human genome proJect promises a one dimensional string of 100 000 genes and sequences, comparative mapping will extend that inference to a second dimension representing index species of the 20 living mammalian orders and to a third dimension by phylogenetic description of the genomes of mammal ancestors. We review here the remarkable extent of genome homology conservation among mammals illustrated by technology applications in the feline genome project.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 393-399 |
| Number of pages | 7 |
| Journal | Trends in Genetics |
| Volume | 13 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1997 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Genetics
Cite this
Comparative genomics : Lessons from cats. / O'Brien, Stephen J.; Wienberg, Johannes; Lyons, Leslie A.
In: Trends in Genetics, Vol. 13, No. 10, 10.1997, p. 393-399.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Comparative genomics
T2 - Lessons from cats
AU - O'Brien, Stephen J.
AU - Wienberg, Johannes
AU - Lyons, Leslie A
PY - 1997/10
Y1 - 1997/10
N2 - The genomics era, spearheaded by dazzling technological developments in human and mouse gene mapping, has additionally provoked extensive comparative gene mapping projects for domestic species of several vertebrate orders. As the human genome proJect promises a one dimensional string of 100 000 genes and sequences, comparative mapping will extend that inference to a second dimension representing index species of the 20 living mammalian orders and to a third dimension by phylogenetic description of the genomes of mammal ancestors. We review here the remarkable extent of genome homology conservation among mammals illustrated by technology applications in the feline genome project.
AB - The genomics era, spearheaded by dazzling technological developments in human and mouse gene mapping, has additionally provoked extensive comparative gene mapping projects for domestic species of several vertebrate orders. As the human genome proJect promises a one dimensional string of 100 000 genes and sequences, comparative mapping will extend that inference to a second dimension representing index species of the 20 living mammalian orders and to a third dimension by phylogenetic description of the genomes of mammal ancestors. We review here the remarkable extent of genome homology conservation among mammals illustrated by technology applications in the feline genome project.
UR - http://www.scopus.com/inward/record.url?scp=0030769509&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030769509&partnerID=8YFLogxK
U2 - 10.1016/S0168-9525(97)01297-3
DO - 10.1016/S0168-9525(97)01297-3
M3 - Review article
C2 - 9351340
AN - SCOPUS:0030769509
VL - 13
SP - 393
EP - 399
JO - Trends in Genetics
JF - Trends in Genetics
SN - 0168-9525
IS - 10
ER -