Comparative analysis of c-reactive protein levels in the saliva and serum of dogs with various diseases

Yoo Ra Cho, Ye In Oh, Gun Ho Song, Young Jun Kim, Kyoung Won Seo

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: We performed this study to characterize the difference between inflammatory and non-inflammatory status in diseased dogs by measurement of salivary C-reactive protein (CRP). In addition, we assessed whether a correlation exists between CRP levels in saliva and those in serum. Materials and Methods: CRP levels were measured in 32 client-owned dogs, which were then divided into inflammation and non-inflammation groups based on serum CRP level. Results: The salivary CRP level was higher in the inflammation group than in the noninflammation group (p < 0.05). Furthermore, there was a positive correlation between salivary and serum CRP levels (R = 0.866, p < 0.001). Conclusion: These data suggest that canine salivary CRP measurements can effectively and non-invasively detect an inflammatory state in dogs.

Original languageEnglish (US)
Pages (from-to)142-147
Number of pages6
JournalInternational Journal of Applied Research in Veterinary Medicine
Volume18
Issue number2
StatePublished - 2021
Externally publishedYes

Keywords

  • C-reactive protein
  • Dogs

ASJC Scopus subject areas

  • veterinary(all)

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