Compact MEMS-based adaptive optics - Optical coherence tomography for clinical use

Diana C. Chen, Scot S. Olivier, Steven M. Jones, Robert J. Zawadzki, Julie W. Evans, Stacey S. Choi, John S. Werner

Research output: Chapter in Book/Report/Conference proceedingConference contribution


We describe a compact MEMS-based adaptive optics (AO) optical coherence tomography (OCT) system with improved AO performance and ease of clinical use. A typical AO system consists of a Shack-Hartmann wavefront sensor and a deformable mirror that measures and corrects the ocular and system aberrations. Because of limitations on current deformable mirror technologies, the amount of real-time ocular-aberration compensation is restricted and small in previous AO-OCT instruments. In this instrument, we incorporate an optical apparatus to correct the spectacle aberrations of the patients such as myopia, hyperopia and astigmatism. This eliminates the tedious process of using trial lenses in clinical imaging. Different amount of spectacle aberration compensation was achieved by motorized stages and automated with the AO computer for ease of clinical use. In addition, the compact AO-OCT was optimized to have minimum system aberrations to reduce AO registration errors and improve AO performance.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 2008
EventMEMS Adaptive Optics II - San Jose, CA, United States
Duration: Jan 22 2008Jan 24 2008


OtherMEMS Adaptive Optics II
Country/TerritoryUnited States
CitySan Jose, CA


  • Adaptive optics
  • Eye
  • Ophthalmic optics
  • Optical coherence tomography
  • Retina

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics


Dive into the research topics of 'Compact MEMS-based adaptive optics - Optical coherence tomography for clinical use'. Together they form a unique fingerprint.

Cite this