Commonly used drugs impair oral tolerance in mice

Sophie Pecquet, Guénolée Prioult, John Campbell, Bruce German, Marco Turini

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Ibuprofen and antibiotics are commonly prescribed during early childhood. When given to mice at the time at which oral tolerance is induced, both treatments affect either the induction or the maintenance of oral tolerance. These results suggest that the coadministration of these and similarly acting drugs should be considered cautiously for infants at risk of allergy.

Original languageEnglish (US)
Pages (from-to)374-378
Number of pages5
JournalAnnals of the New York Academy of Sciences
StatePublished - 2004
Externally publishedYes


  • Allergy
  • Antibiotics
  • Food
  • NSAIDs
  • Oral tolerance
  • Weaning

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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