Common membrane neoantigens on bovine papilloma virus-induced fibroma cells from cattle and horses.

Research output: Contribution to journalArticle

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Abstract

Cultured cells from bovine papilloma virus (BPV)-induced fibroblastic tumors and normal dermis of cattle, horses, and hamsters were examined for cell membrane or internal neoantigens, using the indirect immunofluorescence technique. Sera from cattle and horses bearing BPV-induced fibromas cross reacted with cell membranes of tumor, but not with normal dermal cells of both species. The reaction could be blocked with homologous, but not heterologous, serum of these 2 species. Immunofluorescence was not detected with sera from hamsters bearing BPV-induced sarcomas if incubated with bovine, equine, or hamster cells. Internal neoantigens were not found in any of the acetone-fixed tumor cells, using sera from the 3 species. Both tumor and normal cells were all found free of BPV antigen, using direct immunofluorescence.

Original languageEnglish (US)
Pages (from-to)1643-1645
Number of pages3
JournalAmerican Journal of Veterinary Research
Volume39
Issue number10
StatePublished - Oct 1978
Externally publishedYes

Fingerprint

Bovine papillomavirus
fibroma
Fibroma
Papilloma
Horses
hamsters
fluorescent antibody technique
Viruses
horses
Membranes
cattle
neoplasms
cell membranes
Cricetinae
cells
Serum
dermis
sarcoma
Neoplasms
cultured cells

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Common membrane neoantigens on bovine papilloma virus-induced fibroma cells from cattle and horses. / Barthold, Stephen W; Olson, C.

In: American Journal of Veterinary Research, Vol. 39, No. 10, 10.1978, p. 1643-1645.

Research output: Contribution to journalArticle

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