Abstract
In a recent paper (Spinelli et al 2010 Phys. Med. Biol. 55 483-95) the authors report on their measurements and observations regarding the use of optical imaging of Cerenkov radiation to observe the distribution of radiotracer in a mouse. The paper, while broadly correct, develops a detailed model of the Cerenkov radiation spectrum that does not appropriately consider the particle energy and the distance travelled while velocity exceeds the Cerenkov threshold. Also, we note the authors' two different methods for determining the depth of the source appear in fact to be the same method if the first method properly accounts for the spectrum of the emitted radiation.
| Original language | English (US) |
|---|---|
| Journal | Physics in Medicine and Biology |
| Volume | 55 |
| Issue number | 18 |
| DOIs | |
| State | Published - Sep 21 2010 |
Fingerprint
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
Cite this
Comments on 'cerenkov radiation allows in vivo optical imaging of positron emitting radiotracers'. / Mitchell, Gregory; Gill, R. K.; Cherry, Simon R.
In: Physics in Medicine and Biology, Vol. 55, No. 18, 21.09.2010.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comments on 'cerenkov radiation allows in vivo optical imaging of positron emitting radiotracers'
AU - Mitchell, Gregory
AU - Gill, R. K.
AU - Cherry, Simon R
PY - 2010/9/21
Y1 - 2010/9/21
N2 - In a recent paper (Spinelli et al 2010 Phys. Med. Biol. 55 483-95) the authors report on their measurements and observations regarding the use of optical imaging of Cerenkov radiation to observe the distribution of radiotracer in a mouse. The paper, while broadly correct, develops a detailed model of the Cerenkov radiation spectrum that does not appropriately consider the particle energy and the distance travelled while velocity exceeds the Cerenkov threshold. Also, we note the authors' two different methods for determining the depth of the source appear in fact to be the same method if the first method properly accounts for the spectrum of the emitted radiation.
AB - In a recent paper (Spinelli et al 2010 Phys. Med. Biol. 55 483-95) the authors report on their measurements and observations regarding the use of optical imaging of Cerenkov radiation to observe the distribution of radiotracer in a mouse. The paper, while broadly correct, develops a detailed model of the Cerenkov radiation spectrum that does not appropriately consider the particle energy and the distance travelled while velocity exceeds the Cerenkov threshold. Also, we note the authors' two different methods for determining the depth of the source appear in fact to be the same method if the first method properly accounts for the spectrum of the emitted radiation.
UR - http://www.scopus.com/inward/record.url?scp=78149325366&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78149325366&partnerID=8YFLogxK
U2 - 10.1088/0031-9155/55/18/L01
DO - 10.1088/0031-9155/55/18/L01
M3 - Article
C2 - 20736495
AN - SCOPUS:78149325366
VL - 55
JO - Physics in Medicine and Biology
JF - Physics in Medicine and Biology
SN - 0031-9155
IS - 18
ER -