Comment on Local impermeant anions establish the neuronal chloride concentration

Juha Voipio, Walter F. Boron, Stephen W. Jones, Ulrich Hopfer, John A Payne, Kai Kaila

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Glykys et al. (Reports, 7 February 2014, p. 670) conclude that, rather than ion transporters, "local impermeant anions establish the neuronal chloride concentration" and thereby determine "the magnitude and direction of GABAAR currents at individual synapses." If this were possible, perpetual ion-motion machines could be constructed. The authors' conclusions conflict with basic thermodynamic principles. Copyright

Original languageEnglish (US)
Pages (from-to)1130B
JournalScience
Issue number6201
DOIs
StatePublished - Sep 5 2014

ASJC Scopus subject areas

  • General
  • Medicine(all)

Fingerprint Dive into the research topics of 'Comment on Local impermeant anions establish the neuronal chloride concentration'. Together they form a unique fingerprint.

  • Cite this