Combined vaccine against measles, mumps, rubella, and varicella

P. A. Brunell, V. M. Novelli, S. V. Lipton, Bradley H Pollock

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

A combined measles, mumps, rubella, and varicella vaccine produced seroconversions for all four components similar to that found if measles, mumps, and rubella vaccine or live varicella vaccine were given separately. In addition, those exposed to varicella were completely protected or had only a mild rash. Moreover, the reaction rates were not increased if the vaccines were combined. The somewhat lower and delayed serologic response to live varicella vaccine as compared with the combined measles, mumps, rubella, and varicella may have been due to the small amount of varicella vaccine virus used or to its degree of attenuation. Persistence of antibody was observed 1 year postimmunization.

Original languageEnglish (US)
Pages (from-to)779-784
Number of pages6
JournalPediatrics
Volume81
Issue number6
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Brunell, P. A., Novelli, V. M., Lipton, S. V., & Pollock, B. H. (1988). Combined vaccine against measles, mumps, rubella, and varicella. Pediatrics, 81(6), 779-784.