Abstract
Full characterization or optimization of 2D and 3D PET imaging protocols requires many independent but identically distributed realizations, which can be obtained from simulations of a given scanner. These rely on accurate estimations of single and coincident photon rates, particularly for the fractions of true, scattered and random coincidences recorded. To facilitate such studies, e.g. the combined effect of patient thickness and scan duration on lesion detectability, we propose to combine a photon tracking simulation (SimSET) with a faster analytic projection-based simulation (ASIM). SimSET accurately predicts true, scattered, and random coincidence rates, while ASIM is able to produce the necessary number of realizations with accurate noise properties. We present the simulation modifications and count rate comparisons between real and simulated measurements.
| Original language | English (US) |
|---|---|
| Title of host publication | IEEE Nuclear Science Symposium Conference Record |
| Editors | J.A. Seibert |
| Pages | 3607-3610 |
| Number of pages | 4 |
| Volume | 6 |
| State | Published - 2004 |
| Event | 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy Duration: Oct 16 2004 → Oct 22 2004 |
Other
| Other | 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors |
|---|---|
| Country | Italy |
| City | Rome |
| Period | 10/16/04 → 10/22/04 |
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ASJC Scopus subject areas
- Computer Vision and Pattern Recognition
- Industrial and Manufacturing Engineering
Cite this
Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. / Schmitz, R. E.; Kinahan, P. E.; Harrison, R. L.; Karp, J. S.; Surti, S.; Stearns, C. W.; Badawi, Ramsey D; Lewellen, T. K.
IEEE Nuclear Science Symposium Conference Record. ed. / J.A. Seibert. Vol. 6 2004. p. 3607-3610 M9-271.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols
AU - Schmitz, R. E.
AU - Kinahan, P. E.
AU - Harrison, R. L.
AU - Karp, J. S.
AU - Surti, S.
AU - Stearns, C. W.
AU - Badawi, Ramsey D
AU - Lewellen, T. K.
PY - 2004
Y1 - 2004
N2 - Full characterization or optimization of 2D and 3D PET imaging protocols requires many independent but identically distributed realizations, which can be obtained from simulations of a given scanner. These rely on accurate estimations of single and coincident photon rates, particularly for the fractions of true, scattered and random coincidences recorded. To facilitate such studies, e.g. the combined effect of patient thickness and scan duration on lesion detectability, we propose to combine a photon tracking simulation (SimSET) with a faster analytic projection-based simulation (ASIM). SimSET accurately predicts true, scattered, and random coincidence rates, while ASIM is able to produce the necessary number of realizations with accurate noise properties. We present the simulation modifications and count rate comparisons between real and simulated measurements.
AB - Full characterization or optimization of 2D and 3D PET imaging protocols requires many independent but identically distributed realizations, which can be obtained from simulations of a given scanner. These rely on accurate estimations of single and coincident photon rates, particularly for the fractions of true, scattered and random coincidences recorded. To facilitate such studies, e.g. the combined effect of patient thickness and scan duration on lesion detectability, we propose to combine a photon tracking simulation (SimSET) with a faster analytic projection-based simulation (ASIM). SimSET accurately predicts true, scattered, and random coincidence rates, while ASIM is able to produce the necessary number of realizations with accurate noise properties. We present the simulation modifications and count rate comparisons between real and simulated measurements.
UR - http://www.scopus.com/inward/record.url?scp=23844479302&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=23844479302&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:23844479302
VL - 6
SP - 3607
EP - 3610
BT - IEEE Nuclear Science Symposium Conference Record
A2 - Seibert, J.A.
ER -