Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols

R. E. Schmitz, P. E. Kinahan, R. L. Harrison, J. S. Karp, S. Surti, C. W. Stearns, Ramsey D Badawi, T. K. Lewellen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Full characterization or optimization of 2D and 3D PET imaging protocols requires many independent but identically distributed realizations, which can be obtained from simulations of a given scanner. These rely on accurate estimations of single and coincident photon rates, particularly for the fractions of true, scattered and random coincidences recorded. To facilitate such studies, e.g. the combined effect of patient thickness and scan duration on lesion detectability, we propose to combine a photon tracking simulation (SimSET) with a faster analytic projection-based simulation (ASIM). SimSET accurately predicts true, scattered, and random coincidence rates, while ASIM is able to produce the necessary number of realizations with accurate noise properties. We present the simulation modifications and count rate comparisons between real and simulated measurements.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium Conference Record
EditorsJ.A. Seibert
Pages3607-3610
Number of pages4
Volume6
StatePublished - 2004
Event2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy
Duration: Oct 16 2004Oct 22 2004

Other

Other2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors
CountryItaly
CityRome
Period10/16/0410/22/04

Fingerprint

Photons
Imaging techniques

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Schmitz, R. E., Kinahan, P. E., Harrison, R. L., Karp, J. S., Surti, S., Stearns, C. W., ... Lewellen, T. K. (2004). Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. In J. A. Seibert (Ed.), IEEE Nuclear Science Symposium Conference Record (Vol. 6, pp. 3607-3610). [M9-271]

Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. / Schmitz, R. E.; Kinahan, P. E.; Harrison, R. L.; Karp, J. S.; Surti, S.; Stearns, C. W.; Badawi, Ramsey D; Lewellen, T. K.

IEEE Nuclear Science Symposium Conference Record. ed. / J.A. Seibert. Vol. 6 2004. p. 3607-3610 M9-271.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Schmitz, RE, Kinahan, PE, Harrison, RL, Karp, JS, Surti, S, Stearns, CW, Badawi, RD & Lewellen, TK 2004, Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. in JA Seibert (ed.), IEEE Nuclear Science Symposium Conference Record. vol. 6, M9-271, pp. 3607-3610, 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors, Rome, Italy, 10/16/04.
Schmitz RE, Kinahan PE, Harrison RL, Karp JS, Surti S, Stearns CW et al. Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. In Seibert JA, editor, IEEE Nuclear Science Symposium Conference Record. Vol. 6. 2004. p. 3607-3610. M9-271
Schmitz, R. E. ; Kinahan, P. E. ; Harrison, R. L. ; Karp, J. S. ; Surti, S. ; Stearns, C. W. ; Badawi, Ramsey D ; Lewellen, T. K. / Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. IEEE Nuclear Science Symposium Conference Record. editor / J.A. Seibert. Vol. 6 2004. pp. 3607-3610
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