Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols

R. E. Schmitz; P. E. Kinahan; R. L. Harrison; J. S. Karp; S. Surti; C. W. Stearns; Ramsey D Badawi; T. K. Lewellen

Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols

R. E. Schmitz, P. E. Kinahan, R. L. Harrison, J. S. Karp, S. Surti, C. W. Stearns, Ramsey D Badawi, T. K. Lewellen

Radiology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Full characterization or optimization of 2D and 3D PET imaging protocols requires many independent but identically distributed realizations, which can be obtained from simulations of a given scanner. These rely on accurate estimations of single and coincident photon rates, particularly for the fractions of true, scattered and random coincidences recorded. To facilitate such studies, e.g. the combined effect of patient thickness and scan duration on lesion detectability, we propose to combine a photon tracking simulation (SimSET) with a faster analytic projection-based simulation (ASIM). SimSET accurately predicts true, scattered, and random coincidence rates, while ASIM is able to produce the necessary number of realizations with accurate noise properties. We present the simulation modifications and count rate comparisons between real and simulated measurements.

Original language	English (US)
Title of host publication	IEEE Nuclear Science Symposium Conference Record
Editors	J.A. Seibert
Pages	3607-3610
Number of pages	4
Volume	6
Publication status	Published - 2004
Event	2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy Duration: Oct 16 2004 → Oct 22 2004

Other

Other	2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors
Country	Italy
City	Rome
Period	10/16/04 → 10/22/04

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ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Industrial and Manufacturing Engineering

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Schmitz, R. E., Kinahan, P. E., Harrison, R. L., Karp, J. S., Surti, S., Stearns, C. W., ... Lewellen, T. K. (2004). Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. In J. A. Seibert (Ed.), IEEE Nuclear Science Symposium Conference Record (Vol. 6, pp. 3607-3610). [M9-271]

Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. / Schmitz, R. E.; Kinahan, P. E.; Harrison, R. L.; Karp, J. S.; Surti, S.; Stearns, C. W.; Badawi, Ramsey D; Lewellen, T. K.

IEEE Nuclear Science Symposium Conference Record. ed. / J.A. Seibert. Vol. 6 2004. p. 3607-3610 M9-271.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Schmitz, RE, Kinahan, PE, Harrison, RL, Karp, JS, Surti, S, Stearns, CW, Badawi, RD & Lewellen, TK 2004, Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols. in JA Seibert (ed.), IEEE Nuclear Science Symposium Conference Record. vol. 6, M9-271, pp. 3607-3610, 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors, Rome, Italy, 10/16/04.

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abstract = "Full characterization or optimization of 2D and 3D PET imaging protocols requires many independent but identically distributed realizations, which can be obtained from simulations of a given scanner. These rely on accurate estimations of single and coincident photon rates, particularly for the fractions of true, scattered and random coincidences recorded. To facilitate such studies, e.g. the combined effect of patient thickness and scan duration on lesion detectability, we propose to combine a photon tracking simulation (SimSET) with a faster analytic projection-based simulation (ASIM). SimSET accurately predicts true, scattered, and random coincidence rates, while ASIM is able to produce the necessary number of realizations with accurate noise properties. We present the simulation modifications and count rate comparisons between real and simulated measurements.",

author = "Schmitz, {R. E.} and Kinahan, {P. E.} and Harrison, {R. L.} and Karp, {J. S.} and S. Surti and Stearns, {C. W.} and Badawi, {Ramsey D} and Lewellen, {T. K.}",

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AU - Surti, S.

AU - Stearns, C. W.

AU - Badawi, Ramsey D

AU - Lewellen, T. K.

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AB - Full characterization or optimization of 2D and 3D PET imaging protocols requires many independent but identically distributed realizations, which can be obtained from simulations of a given scanner. These rely on accurate estimations of single and coincident photon rates, particularly for the fractions of true, scattered and random coincidences recorded. To facilitate such studies, e.g. the combined effect of patient thickness and scan duration on lesion detectability, we propose to combine a photon tracking simulation (SimSET) with a faster analytic projection-based simulation (ASIM). SimSET accurately predicts true, scattered, and random coincidence rates, while ASIM is able to produce the necessary number of realizations with accurate noise properties. We present the simulation modifications and count rate comparisons between real and simulated measurements.

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Combined simulations for evaluation of 2D and 3D wholebody PET imaging protocols

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