Combination chemotherapy in a prostate tumor model: Nb rat prostatic adenocarcinoma model

J. R. Drago, T. Worgul, M. Eric Gershwin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

This report presents the experience with single and combination chemotherapy in the Noble rat prostatic adenocarcinoma model. The best single agent in treatment of these tumors is cyclophosphamide, the best combination was triple drug therapy cyclophosphamide, cis-platinum, and adriamycin. This report examines the effect of the various chemotherapeutic regimens on tumor volume, number of metastases, and complete tumor regression.

Original languageEnglish (US)
Pages (from-to)353-363
Number of pages11
JournalJournal of Surgical Oncology
Volume16
Issue number4
StatePublished - 1981

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Combination Drug Therapy
Cyclophosphamide
Prostate
Adenocarcinoma
Tumor Burden
Doxorubicin
Cisplatin
Neoplasms
Neoplasm Metastasis
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

Combination chemotherapy in a prostate tumor model : Nb rat prostatic adenocarcinoma model. / Drago, J. R.; Worgul, T.; Gershwin, M. Eric.

In: Journal of Surgical Oncology, Vol. 16, No. 4, 1981, p. 353-363.

Research output: Contribution to journalArticle

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