Colorectal Surgery in Patients with HIV and AIDS: Trends and Outcomes over a 10-Year Period in the USA

John V. Gahagan, Wissam J Halabi, Vinh Q. Nguyen, Joseph C. Carmichael, Alessio Pigazzi, Michael J. Stamos, Steven D. Mills

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: HIV has become a chronic disease, which may render this population more prone to developing the colorectal pathologies that typically affect older Americans. Methods: A retrospective review of the Nationwide Inpatient Sample was performed to identify patients who underwent colon and rectal surgery from 2001 to 2010. Multivariate analysis was used to evaluate outcomes among the general population, patients with HIV, and patients with AIDS. Results: Hospital admissions for colon and rectal procedures of patients with HIV/AIDS grew at a faster rate than all-cause admissions of patients with HIV/AIDS, with mean yearly increases of 17.8 and 2.1 %, respectively (p < 0.05). Patients with HIV/AIDS undergoing colon and rectal operations for cancer, polyps, diverticular disease, and Clostridium difficile were younger than the general population (51 vs. 65 years; p < 0.01). AIDS was independently associated with increased odds of mortality (OR 2.11; 95 % CI 1.24, 3.61), wound complications (OR 1.53; 95 % CI 1.09, 2.17), and pneumonia (OR 2.02; 95 % CI 1.33, 3.08). Risk-adjusted outcomes of colorectal surgery in patients with HIV did not differ significantly from the general population. Conclusion: Postoperative outcomes in patients with HIV are similar to the general population, while patients with AIDS have a higher risk of mortality and certain complications.

Original languageEnglish (US)
Pages (from-to)1239-1246
Number of pages8
JournalJournal of Gastrointestinal Surgery
Volume20
Issue number6
DOIs
StatePublished - Jun 1 2016
Externally publishedYes

Fingerprint

Colorectal Surgery
Acquired Immunodeficiency Syndrome
HIV
Colon
Population
Clostridium difficile
Mortality
Patient Admission
Rectal Neoplasms
Polyps
Inpatients
Pneumonia
Chronic Disease
Multivariate Analysis
Pathology
Wounds and Injuries

Keywords

  • AIDS
  • Colorectal
  • HIV
  • Outcomes

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

Cite this

Colorectal Surgery in Patients with HIV and AIDS : Trends and Outcomes over a 10-Year Period in the USA. / Gahagan, John V.; Halabi, Wissam J; Nguyen, Vinh Q.; Carmichael, Joseph C.; Pigazzi, Alessio; Stamos, Michael J.; Mills, Steven D.

In: Journal of Gastrointestinal Surgery, Vol. 20, No. 6, 01.06.2016, p. 1239-1246.

Research output: Contribution to journalArticle

Gahagan, John V. ; Halabi, Wissam J ; Nguyen, Vinh Q. ; Carmichael, Joseph C. ; Pigazzi, Alessio ; Stamos, Michael J. ; Mills, Steven D. / Colorectal Surgery in Patients with HIV and AIDS : Trends and Outcomes over a 10-Year Period in the USA. In: Journal of Gastrointestinal Surgery. 2016 ; Vol. 20, No. 6. pp. 1239-1246.
@article{5efa7b31875a47cb83e31c0d15857c1a,
title = "Colorectal Surgery in Patients with HIV and AIDS: Trends and Outcomes over a 10-Year Period in the USA",
abstract = "Background: HIV has become a chronic disease, which may render this population more prone to developing the colorectal pathologies that typically affect older Americans. Methods: A retrospective review of the Nationwide Inpatient Sample was performed to identify patients who underwent colon and rectal surgery from 2001 to 2010. Multivariate analysis was used to evaluate outcomes among the general population, patients with HIV, and patients with AIDS. Results: Hospital admissions for colon and rectal procedures of patients with HIV/AIDS grew at a faster rate than all-cause admissions of patients with HIV/AIDS, with mean yearly increases of 17.8 and 2.1 {\%}, respectively (p < 0.05). Patients with HIV/AIDS undergoing colon and rectal operations for cancer, polyps, diverticular disease, and Clostridium difficile were younger than the general population (51 vs. 65 years; p < 0.01). AIDS was independently associated with increased odds of mortality (OR 2.11; 95 {\%} CI 1.24, 3.61), wound complications (OR 1.53; 95 {\%} CI 1.09, 2.17), and pneumonia (OR 2.02; 95 {\%} CI 1.33, 3.08). Risk-adjusted outcomes of colorectal surgery in patients with HIV did not differ significantly from the general population. Conclusion: Postoperative outcomes in patients with HIV are similar to the general population, while patients with AIDS have a higher risk of mortality and certain complications.",
keywords = "AIDS, Colorectal, HIV, Outcomes",
author = "Gahagan, {John V.} and Halabi, {Wissam J} and Nguyen, {Vinh Q.} and Carmichael, {Joseph C.} and Alessio Pigazzi and Stamos, {Michael J.} and Mills, {Steven D.}",
year = "2016",
month = "6",
day = "1",
doi = "10.1007/s11605-016-3119-x",
language = "English (US)",
volume = "20",
pages = "1239--1246",
journal = "Journal of Gastrointestinal Surgery",
issn = "1091-255X",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - Colorectal Surgery in Patients with HIV and AIDS

T2 - Trends and Outcomes over a 10-Year Period in the USA

AU - Gahagan, John V.

AU - Halabi, Wissam J

AU - Nguyen, Vinh Q.

AU - Carmichael, Joseph C.

AU - Pigazzi, Alessio

AU - Stamos, Michael J.

AU - Mills, Steven D.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Background: HIV has become a chronic disease, which may render this population more prone to developing the colorectal pathologies that typically affect older Americans. Methods: A retrospective review of the Nationwide Inpatient Sample was performed to identify patients who underwent colon and rectal surgery from 2001 to 2010. Multivariate analysis was used to evaluate outcomes among the general population, patients with HIV, and patients with AIDS. Results: Hospital admissions for colon and rectal procedures of patients with HIV/AIDS grew at a faster rate than all-cause admissions of patients with HIV/AIDS, with mean yearly increases of 17.8 and 2.1 %, respectively (p < 0.05). Patients with HIV/AIDS undergoing colon and rectal operations for cancer, polyps, diverticular disease, and Clostridium difficile were younger than the general population (51 vs. 65 years; p < 0.01). AIDS was independently associated with increased odds of mortality (OR 2.11; 95 % CI 1.24, 3.61), wound complications (OR 1.53; 95 % CI 1.09, 2.17), and pneumonia (OR 2.02; 95 % CI 1.33, 3.08). Risk-adjusted outcomes of colorectal surgery in patients with HIV did not differ significantly from the general population. Conclusion: Postoperative outcomes in patients with HIV are similar to the general population, while patients with AIDS have a higher risk of mortality and certain complications.

AB - Background: HIV has become a chronic disease, which may render this population more prone to developing the colorectal pathologies that typically affect older Americans. Methods: A retrospective review of the Nationwide Inpatient Sample was performed to identify patients who underwent colon and rectal surgery from 2001 to 2010. Multivariate analysis was used to evaluate outcomes among the general population, patients with HIV, and patients with AIDS. Results: Hospital admissions for colon and rectal procedures of patients with HIV/AIDS grew at a faster rate than all-cause admissions of patients with HIV/AIDS, with mean yearly increases of 17.8 and 2.1 %, respectively (p < 0.05). Patients with HIV/AIDS undergoing colon and rectal operations for cancer, polyps, diverticular disease, and Clostridium difficile were younger than the general population (51 vs. 65 years; p < 0.01). AIDS was independently associated with increased odds of mortality (OR 2.11; 95 % CI 1.24, 3.61), wound complications (OR 1.53; 95 % CI 1.09, 2.17), and pneumonia (OR 2.02; 95 % CI 1.33, 3.08). Risk-adjusted outcomes of colorectal surgery in patients with HIV did not differ significantly from the general population. Conclusion: Postoperative outcomes in patients with HIV are similar to the general population, while patients with AIDS have a higher risk of mortality and certain complications.

KW - AIDS

KW - Colorectal

KW - HIV

KW - Outcomes

UR - http://www.scopus.com/inward/record.url?scp=84960081262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84960081262&partnerID=8YFLogxK

U2 - 10.1007/s11605-016-3119-x

DO - 10.1007/s11605-016-3119-x

M3 - Article

C2 - 26940943

AN - SCOPUS:84960081262

VL - 20

SP - 1239

EP - 1246

JO - Journal of Gastrointestinal Surgery

JF - Journal of Gastrointestinal Surgery

SN - 1091-255X

IS - 6

ER -