Colonic volvulus in the United States: Trends, outcomes, and predictors of mortality

Wissam J Halabi, Mehraneh D. Jafari, Celeste Y. Kang, Vinh Q. Nguyen, Joseph C. Carmichael, Steven Mills, Alessio Pigazzi, Michael J. Stamos

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

INTRODUCTION:: Colonic volvulus is a rare entity associated with high mortality rates. Most studies come from areas of high endemicity and are limited by small numbers. No studies have investigated trends, outcomes, and predictors of mortality at the national level. METHODS:: The Nationwide Inpatient Sample 2002-2010 was retrospectively reviewed for colonic volvulus cases admitted emergently. Patients' demographics, hospital factors, and outcomes of the different procedures were analyzed. The LASSO algorithm for logistic regression was used to build a predictive model for mortality in cases of sigmoid (SV) and cecal volvulus (CV) taking into account preoperative and operative variables. RESULTS:: An estimated 3,351,152 cases of bowel obstruction were admitted in the United States over the study period. Colonic volvulus was found to be the cause in 63,749 cases (1.90%). The incidence of CV increased by 5.53% per year whereas the incidence of SV remained stable. SV was more common in elderly males (aged 70 years), African Americans, and patients with diabetes and neuropsychiatric disorders. In contrast, CV was more common in younger females. Nonsurgical decompression alone was used in 17% of cases. Among cases managed surgically, resective procedures were performed in 89% of cases, whereas operative detorsion with or without fixation procedures remained uncommon. Mortality rates were 9.44% for SV, 6.64% for CV, 17% for synchronous CV and SV, and 18% for transverse colon volvulus. The LASSO algorithm identified bowel gangrene and peritonitis, coagulopathy, age, the use of stoma, and chronic kidney disease as strong predictors of mortality. CONCLUSIONS:: Colonic volvulus is a rare cause of bowel obstruction in the United States and is associated with high mortality rates. CV and SV affect different populations and the incidence of CV is on the rise. The presence of bowel gangrene and coagulopathy strongly predicts mortality, suggesting that prompt diagnosis and management are essential.

Original languageEnglish (US)
Pages (from-to)293-301
Number of pages9
JournalAnnals of Surgery
Volume259
Issue number2
DOIs
StatePublished - Feb 1 2014
Externally publishedYes

Fingerprint

Intestinal Volvulus
Mortality
Gangrene
Incidence
Transverse Colon
Sigmoid Colon
Decompression
Peritonitis
Chronic Renal Insufficiency
African Americans
Inpatients
Logistic Models

Keywords

  • cecal volvulus
  • mortality
  • sigmoid volvulus
  • transverse colon volvulus
  • trends

ASJC Scopus subject areas

  • Surgery

Cite this

Halabi, W. J., Jafari, M. D., Kang, C. Y., Nguyen, V. Q., Carmichael, J. C., Mills, S., ... Stamos, M. J. (2014). Colonic volvulus in the United States: Trends, outcomes, and predictors of mortality. Annals of Surgery, 259(2), 293-301. https://doi.org/10.1097/SLA.0b013e31828c88ac

Colonic volvulus in the United States : Trends, outcomes, and predictors of mortality. / Halabi, Wissam J; Jafari, Mehraneh D.; Kang, Celeste Y.; Nguyen, Vinh Q.; Carmichael, Joseph C.; Mills, Steven; Pigazzi, Alessio; Stamos, Michael J.

In: Annals of Surgery, Vol. 259, No. 2, 01.02.2014, p. 293-301.

Research output: Contribution to journalArticle

Halabi, WJ, Jafari, MD, Kang, CY, Nguyen, VQ, Carmichael, JC, Mills, S, Pigazzi, A & Stamos, MJ 2014, 'Colonic volvulus in the United States: Trends, outcomes, and predictors of mortality', Annals of Surgery, vol. 259, no. 2, pp. 293-301. https://doi.org/10.1097/SLA.0b013e31828c88ac
Halabi, Wissam J ; Jafari, Mehraneh D. ; Kang, Celeste Y. ; Nguyen, Vinh Q. ; Carmichael, Joseph C. ; Mills, Steven ; Pigazzi, Alessio ; Stamos, Michael J. / Colonic volvulus in the United States : Trends, outcomes, and predictors of mortality. In: Annals of Surgery. 2014 ; Vol. 259, No. 2. pp. 293-301.
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abstract = "INTRODUCTION:: Colonic volvulus is a rare entity associated with high mortality rates. Most studies come from areas of high endemicity and are limited by small numbers. No studies have investigated trends, outcomes, and predictors of mortality at the national level. METHODS:: The Nationwide Inpatient Sample 2002-2010 was retrospectively reviewed for colonic volvulus cases admitted emergently. Patients' demographics, hospital factors, and outcomes of the different procedures were analyzed. The LASSO algorithm for logistic regression was used to build a predictive model for mortality in cases of sigmoid (SV) and cecal volvulus (CV) taking into account preoperative and operative variables. RESULTS:: An estimated 3,351,152 cases of bowel obstruction were admitted in the United States over the study period. Colonic volvulus was found to be the cause in 63,749 cases (1.90{\%}). The incidence of CV increased by 5.53{\%} per year whereas the incidence of SV remained stable. SV was more common in elderly males (aged 70 years), African Americans, and patients with diabetes and neuropsychiatric disorders. In contrast, CV was more common in younger females. Nonsurgical decompression alone was used in 17{\%} of cases. Among cases managed surgically, resective procedures were performed in 89{\%} of cases, whereas operative detorsion with or without fixation procedures remained uncommon. Mortality rates were 9.44{\%} for SV, 6.64{\%} for CV, 17{\%} for synchronous CV and SV, and 18{\%} for transverse colon volvulus. The LASSO algorithm identified bowel gangrene and peritonitis, coagulopathy, age, the use of stoma, and chronic kidney disease as strong predictors of mortality. CONCLUSIONS:: Colonic volvulus is a rare cause of bowel obstruction in the United States and is associated with high mortality rates. CV and SV affect different populations and the incidence of CV is on the rise. The presence of bowel gangrene and coagulopathy strongly predicts mortality, suggesting that prompt diagnosis and management are essential.",
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N2 - INTRODUCTION:: Colonic volvulus is a rare entity associated with high mortality rates. Most studies come from areas of high endemicity and are limited by small numbers. No studies have investigated trends, outcomes, and predictors of mortality at the national level. METHODS:: The Nationwide Inpatient Sample 2002-2010 was retrospectively reviewed for colonic volvulus cases admitted emergently. Patients' demographics, hospital factors, and outcomes of the different procedures were analyzed. The LASSO algorithm for logistic regression was used to build a predictive model for mortality in cases of sigmoid (SV) and cecal volvulus (CV) taking into account preoperative and operative variables. RESULTS:: An estimated 3,351,152 cases of bowel obstruction were admitted in the United States over the study period. Colonic volvulus was found to be the cause in 63,749 cases (1.90%). The incidence of CV increased by 5.53% per year whereas the incidence of SV remained stable. SV was more common in elderly males (aged 70 years), African Americans, and patients with diabetes and neuropsychiatric disorders. In contrast, CV was more common in younger females. Nonsurgical decompression alone was used in 17% of cases. Among cases managed surgically, resective procedures were performed in 89% of cases, whereas operative detorsion with or without fixation procedures remained uncommon. Mortality rates were 9.44% for SV, 6.64% for CV, 17% for synchronous CV and SV, and 18% for transverse colon volvulus. The LASSO algorithm identified bowel gangrene and peritonitis, coagulopathy, age, the use of stoma, and chronic kidney disease as strong predictors of mortality. CONCLUSIONS:: Colonic volvulus is a rare cause of bowel obstruction in the United States and is associated with high mortality rates. CV and SV affect different populations and the incidence of CV is on the rise. The presence of bowel gangrene and coagulopathy strongly predicts mortality, suggesting that prompt diagnosis and management are essential.

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