Colonic Intussusception in a Rabbit

A specific-pathogen-free New Zealand White Rabbit used in a standard polyclonal antibody protocol developed anorexia and diarrhea. Results of clinical examination and radiography suggested a mid-abdominal mass. At necropsy, a colonic intussusception was found. Microbiologic, microscopic, and fecal flotation examinations failed to reveal a primary pathogen. Previously reported intussusception cases were associated with coccidiosis. Because evidence of a primary pathogen was not found in this case, one should also consider the role(s) of motility modifying compounds and immunization-induced stress in intussusceptions in rabbits. Our findings underscore the importance of performing a thorough physical examination and judicious use of pharmacologic intervention in evaluating and managing gastrointestinal disease in rabbits.