Colonic adenomas

Stereology and growth mechanisms

H. Elias, D. M. Hyde, R. S. Mullens, F. C. Lambert

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Stereologic methods were used to determine the amount of growth of colonic adenomatous polyps. Epithelial surfaces were increased from 12 to 226 times compared with the normal mucosa of origin, including the epithelium of the crypts. The number of cells was increased from 12 to 370 times. The supposed villi of the polyps are in reality branched folia, and the crypts between them are slit-like, permitting flow of ingesta through them. The increase in the number of cells is not primarily dependent on mitotic activity but more on amitotic nuclear fragmentation.

Original languageEnglish (US)
Pages (from-to)331-342
Number of pages12
JournalDiseases of the Colon and Rectum
Volume24
Issue number5
StatePublished - 1981

Fingerprint

Adenoma
Cell Count
Colonic Polyps
Adenomatous Polyps
Growth
Polyps
Mucous Membrane
Epithelium

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Elias, H., Hyde, D. M., Mullens, R. S., & Lambert, F. C. (1981). Colonic adenomas: Stereology and growth mechanisms. Diseases of the Colon and Rectum, 24(5), 331-342.

Colonic adenomas : Stereology and growth mechanisms. / Elias, H.; Hyde, D. M.; Mullens, R. S.; Lambert, F. C.

In: Diseases of the Colon and Rectum, Vol. 24, No. 5, 1981, p. 331-342.

Research output: Contribution to journalArticle

Elias, H, Hyde, DM, Mullens, RS & Lambert, FC 1981, 'Colonic adenomas: Stereology and growth mechanisms', Diseases of the Colon and Rectum, vol. 24, no. 5, pp. 331-342.
Elias H, Hyde DM, Mullens RS, Lambert FC. Colonic adenomas: Stereology and growth mechanisms. Diseases of the Colon and Rectum. 1981;24(5):331-342.
Elias, H. ; Hyde, D. M. ; Mullens, R. S. ; Lambert, F. C. / Colonic adenomas : Stereology and growth mechanisms. In: Diseases of the Colon and Rectum. 1981 ; Vol. 24, No. 5. pp. 331-342.
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