Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta)

Eugene H. Johnson, Susan E. Morgenstern, Jill M. Perham, Stephen W Barthold

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.

Original languageEnglish (US)
Pages (from-to)435-438
Number of pages4
JournalJournal of Medical Primatology
Volume25
Issue number6
StatePublished - Dec 1996
Externally publishedYes

Keywords

  • CA-125
  • Colonic adenocarcinoma
  • Endometriosis
  • Rhesus macaque

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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  • Cite this

    Johnson, E. H., Morgenstern, S. E., Perham, J. M., & Barthold, S. W. (1996). Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta). Journal of Medical Primatology, 25(6), 435-438.