Collecting and organizing systematic sets of protein data

John Albeck, Gavin MacBeath, Forest M. White, Peter K. Sorger, Douglas A. Lauffenburger, Suzanne Gaudet

Research output: Contribution to journalReview article

88 Scopus citations

Abstract

Systems biology, particularly of mammalian cells, is data starved. However, technologies are now in place to obtain rich data, in a form suitable for model construction and validation, that describes the activities, states and locations of cell-signalling molecules. The key is to use several measurement technologies simultaneously and, recognizing each of their limits, to assemble a self-consistent compendium of systematic data.

Original languageEnglish (US)
Pages (from-to)803-812
Number of pages10
JournalNature Reviews Molecular Cell Biology
Volume7
Issue number11
DOIs
StatePublished - Nov 1 2006
Externally publishedYes

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ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Cite this

Albeck, J., MacBeath, G., White, F. M., Sorger, P. K., Lauffenburger, D. A., & Gaudet, S. (2006). Collecting and organizing systematic sets of protein data. Nature Reviews Molecular Cell Biology, 7(11), 803-812. https://doi.org/10.1038/nrm2042