Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava

Kristina W. Calicchio, R. Avery Bennett, Leonard C. Laraio, Chick Weisse, Allison Zwingenberger, Karen L. Rosenthal, Matthew S. Johnston, Vicki L. Campbell, Jeffrey A. Solomon

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Abstract

OBJECTIVE To determine whether extent of collateral circulation would change during temporary occlusion of the caudal vena cava (CVC) in ferrets (Mustela putorius), a pressure change would occur caudal to the occlusion, and differences would exist between the sexes with respect to those changes. ANIMALS 8 adult ferrets (4 castrated males and 4 spayed females). PROCEDURES Ferrets were anesthetized. A balloon occlusion catheter was introduced through a jugular vein, passed into the CVC by use of fluoroscopy, positioned cranial to the right renal vein, and inflated for 20 minutes. Venography was performed 5 and 15 minutes after occlusion. Pressure in the CVC caudal to the occlusion was measured continuously. A CBC, plasma biochemical analysis, and urinalysis were performed immediately after the procedure and 2 or 3 days later. RESULTS All 8 ferrets survived the procedure; no differences were apparent between the sexes. Vessels providing collateral circulation were identified in all ferrets, indicating blood flow to the paravertebral venous plexus. Complications observed prior to occlusion included atrial and ventricular premature contractions. Complications after occlusion included bradycardia, seizures, and extravasation of contrast medium. Mean baseline CVC pressure was 5.4 cm H2O. During occlusion, 6 ferrets had a moderate increase in CVC pressure (mean, 24.3 cm H2O) and 2 ferrets had a marked increase in CVC pressure to > 55.0 cm H2O. CONCLUSIONS AND CLINICAL RELEVANCE Caval occlusion for 20 minutes was performed in healthy ferrets with minimal adverse effects noted within the follow-up period and no apparent differences between sexes. The CVC pressure during occlusion may be prognostic in ferrets undergoing surgical ligation of the CVC, which commonly occurs during adrenal tumor resection.

Original languageEnglish (US)
Pages (from-to)540-547
Number of pages8
JournalAmerican Journal of Veterinary Research
Volume77
Issue number5
StatePublished - May 1 2016

Fingerprint

Mustela putorius
vena cava
Collateral Circulation
Ferrets
Venae Cavae
ferrets
Pressure
gender
Extravasation of Diagnostic and Therapeutic Materials
Atrial Premature Complexes
urinalysis
Balloon Occlusion
plexus
jugular vein
Renal Veins
Urinalysis
Glandular and Epithelial Neoplasms
Ventricular Premature Complexes
resection
seizures

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Calicchio, K. W., Bennett, R. A., Laraio, L. C., Weisse, C., Zwingenberger, A., Rosenthal, K. L., ... Solomon, J. A. (2016). Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava. American Journal of Veterinary Research, 77(5), 540-547.

Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava. / Calicchio, Kristina W.; Bennett, R. Avery; Laraio, Leonard C.; Weisse, Chick; Zwingenberger, Allison; Rosenthal, Karen L.; Johnston, Matthew S.; Campbell, Vicki L.; Solomon, Jeffrey A.

In: American Journal of Veterinary Research, Vol. 77, No. 5, 01.05.2016, p. 540-547.

Research output: Contribution to journalArticle

Calicchio, KW, Bennett, RA, Laraio, LC, Weisse, C, Zwingenberger, A, Rosenthal, KL, Johnston, MS, Campbell, VL & Solomon, JA 2016, 'Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava', American Journal of Veterinary Research, vol. 77, no. 5, pp. 540-547.
Calicchio, Kristina W. ; Bennett, R. Avery ; Laraio, Leonard C. ; Weisse, Chick ; Zwingenberger, Allison ; Rosenthal, Karen L. ; Johnston, Matthew S. ; Campbell, Vicki L. ; Solomon, Jeffrey A. / Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava. In: American Journal of Veterinary Research. 2016 ; Vol. 77, No. 5. pp. 540-547.
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AU - Johnston, Matthew S.

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