Coinfection with Clostridium piliforme and Felid herpesvirus 1 in a kitten

Rachel T. Neto, Francisco A. Uzal, Emir Hodzic, Michele Persiani, Shazia Jolissaint, Ana Alcaraz, Francisco R. Carvallo

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A 1-month-old Domestic Shorthair kitten was submitted for autopsy, with a history of upper respiratory tract infection and diarrhea. This was the third kitten from the same litter that had died with similar clinical findings within a period of 1 month. Severe conjunctivitis, rhinitis, tracheitis, and bronchointerstitial pneumonia were present, together with lymphohistiocytic colitis. Respiratory lesions were caused by infection with Felid herpesvirus 1. Colonic lesions were associated with the presence of long filamentous bacteria, identified as Clostridium piliforme, in the cytoplasm of epithelial cells. Our report describes a case of concurrent C. piliforme infection (Tyzzer’s disease) and feline rhinotracheitis in a kitten.

Original languageEnglish (US)
Pages (from-to)547-551
Number of pages5
JournalJournal of Veterinary Diagnostic Investigation
Issue number4
StatePublished - Jul 4 2015


  • Colitis
  • feline
  • rhinotracheitis
  • Tyzzer’s disease

ASJC Scopus subject areas

  • veterinary(all)


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