Cognitive predictors of functional decline in vascular dementia

Angela L. Jefferson, Deborah Cahn-Weiner, Patricia Boyle, Robert H. Paul, David J. Moser, Norman Gordon, Ronald A. Cohen

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Background: This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year. Methods: Twenty-four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant-based measure of instrumental (IADL) and basic activities of daily living (BADL). Follow-up assessment was conducted one-year post-baseline. Results: Logistic regression revealed that changes in the DRS Initiation/Perseveration and DRS Memory subscales were significantly associated with declines in IADLs and BADLs, respectively. Conclusions: Among patients with VaD, longitudinal changes in IADLs and BADLs are most strongly associated with changes in executive functioning and memory abilities, respectively. Findings suggest that different cognitive functions subserve complex instrumental and rote, habituated basic functional activities, and neuropsychological screening measures are useful in the prediction of such functional changes.

Original languageEnglish (US)
Pages (from-to)752-754
Number of pages3
JournalInternational Journal of Geriatric Psychiatry
Volume21
Issue number8
DOIs
StatePublished - Aug 1 2006
Externally publishedYes

Keywords

  • Activities of daily living (ADLs)
  • Cognition
  • Dementia Rating Scale (DRS)
  • Executive function
  • Functional decline
  • Memory
  • Neuropsychology
  • Vascular dementia (VaD)

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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  • Cite this

    Jefferson, A. L., Cahn-Weiner, D., Boyle, P., Paul, R. H., Moser, D. J., Gordon, N., & Cohen, R. A. (2006). Cognitive predictors of functional decline in vascular dementia. International Journal of Geriatric Psychiatry, 21(8), 752-754. https://doi.org/10.1002/gps.1556