Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction

Christopher I. Higginson, Vicki L Wheelock, Dawn Levine, David S. King, Conrad T E Pappas, Karen A. Sigvardt

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Essential tremor (ET) is increasingly thought to involve a heterogeneous group of patients, with some also exhibiting symptoms of Parkinson's disease (PD), including cognitive deficits. The goal of this study was to utilize a broad battery of neuropsychological measures to compare the cognitive function of 33 ET patients with that of 33 matched PD patients and 21 normal controls. Results indicated that the ET group performed significantly worse than controls across multiple cognitive domains, but performed remarkably similar to PD patients, consistent with frontosubcortical dysfunction.

Original languageEnglish (US)
Pages (from-to)760-765
Number of pages6
JournalJournal of Clinical and Experimental Neuropsychology
Volume30
Issue number7
DOIs
StatePublished - Feb 2008

Fingerprint

Essential Tremor
Parkinson Disease
Cognition

Keywords

  • Cognitive function
  • Essential tremor
  • Movement disorder
  • Neuropsychology
  • Parkinson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychology(all)
  • Clinical Psychology

Cite this

Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction. / Higginson, Christopher I.; Wheelock, Vicki L; Levine, Dawn; King, David S.; Pappas, Conrad T E; Sigvardt, Karen A.

In: Journal of Clinical and Experimental Neuropsychology, Vol. 30, No. 7, 02.2008, p. 760-765.

Research output: Contribution to journalArticle

Higginson, Christopher I. ; Wheelock, Vicki L ; Levine, Dawn ; King, David S. ; Pappas, Conrad T E ; Sigvardt, Karen A. / Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction. In: Journal of Clinical and Experimental Neuropsychology. 2008 ; Vol. 30, No. 7. pp. 760-765.
@article{47cf3547835b40c78a082910bb2e997f,
title = "Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction",
abstract = "Essential tremor (ET) is increasingly thought to involve a heterogeneous group of patients, with some also exhibiting symptoms of Parkinson's disease (PD), including cognitive deficits. The goal of this study was to utilize a broad battery of neuropsychological measures to compare the cognitive function of 33 ET patients with that of 33 matched PD patients and 21 normal controls. Results indicated that the ET group performed significantly worse than controls across multiple cognitive domains, but performed remarkably similar to PD patients, consistent with frontosubcortical dysfunction.",
keywords = "Cognitive function, Essential tremor, Movement disorder, Neuropsychology, Parkinson's disease",
author = "Higginson, {Christopher I.} and Wheelock, {Vicki L} and Dawn Levine and King, {David S.} and Pappas, {Conrad T E} and Sigvardt, {Karen A.}",
year = "2008",
month = "2",
doi = "10.1080/13803390701754738",
language = "English (US)",
volume = "30",
pages = "760--765",
journal = "Journal of Clinical and Experimental Neuropsychology",
issn = "1380-3395",
publisher = "Psychology Press Ltd",
number = "7",

}

TY - JOUR

T1 - Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction

AU - Higginson, Christopher I.

AU - Wheelock, Vicki L

AU - Levine, Dawn

AU - King, David S.

AU - Pappas, Conrad T E

AU - Sigvardt, Karen A.

PY - 2008/2

Y1 - 2008/2

N2 - Essential tremor (ET) is increasingly thought to involve a heterogeneous group of patients, with some also exhibiting symptoms of Parkinson's disease (PD), including cognitive deficits. The goal of this study was to utilize a broad battery of neuropsychological measures to compare the cognitive function of 33 ET patients with that of 33 matched PD patients and 21 normal controls. Results indicated that the ET group performed significantly worse than controls across multiple cognitive domains, but performed remarkably similar to PD patients, consistent with frontosubcortical dysfunction.

AB - Essential tremor (ET) is increasingly thought to involve a heterogeneous group of patients, with some also exhibiting symptoms of Parkinson's disease (PD), including cognitive deficits. The goal of this study was to utilize a broad battery of neuropsychological measures to compare the cognitive function of 33 ET patients with that of 33 matched PD patients and 21 normal controls. Results indicated that the ET group performed significantly worse than controls across multiple cognitive domains, but performed remarkably similar to PD patients, consistent with frontosubcortical dysfunction.

KW - Cognitive function

KW - Essential tremor

KW - Movement disorder

KW - Neuropsychology

KW - Parkinson's disease

UR - http://www.scopus.com/inward/record.url?scp=51349110231&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=51349110231&partnerID=8YFLogxK

U2 - 10.1080/13803390701754738

DO - 10.1080/13803390701754738

M3 - Article

VL - 30

SP - 760

EP - 765

JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

SN - 1380-3395

IS - 7

ER -