Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction

Christopher I. Higginson, Vicki L Wheelock, Dawn Levine, David S. King, Conrad T E Pappas, Karen A. Sigvardt

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Essential tremor (ET) is increasingly thought to involve a heterogeneous group of patients, with some also exhibiting symptoms of Parkinson's disease (PD), including cognitive deficits. The goal of this study was to utilize a broad battery of neuropsychological measures to compare the cognitive function of 33 ET patients with that of 33 matched PD patients and 21 normal controls. Results indicated that the ET group performed significantly worse than controls across multiple cognitive domains, but performed remarkably similar to PD patients, consistent with frontosubcortical dysfunction.

Original languageEnglish (US)
Pages (from-to)760-765
Number of pages6
JournalJournal of Clinical and Experimental Neuropsychology
Issue number7
StatePublished - Feb 2008


  • Cognitive function
  • Essential tremor
  • Movement disorder
  • Neuropsychology
  • Parkinson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychology(all)
  • Clinical Psychology


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