Cognitive and affective changes after myelography: A comparison of metrizamide and lohexol

G. Ratcliff, S. Sandler, Richard E Latchaw

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A battery of brief cognitive tests and a mood scale were administered to 42 patients before and after cervical myelography with either metrizamide (20 patients) or iohexol (22 patients). The patients receiving metrizamide experienced a deterioration in mood after myelography and a relatively greater decline in cognitive test performance than did those receiving iohexol. These two side effects tended to occur together in the metrizamide group, suggesting a common underlying cause; but there was no correlation between changes in mood and cognitive function after myelography with iohexol. These results suggest that metrizamide has a greater neurotoxic effect than iohexol.

Original languageEnglish (US)
Pages (from-to)777-781
Number of pages5
JournalAmerican Journal of Roentgenology
Volume147
Issue number4
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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