Cocoa, chocolate, and cardiovascular disease

Monica Galleano, Patricia I. Oteiza, Cesar G. Fraga

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

A significant body of evidence demonstrates that diets rich in fruits and vegetables promote health and attenuate, or delay, the onset of various diseases, including cardiovascular disease, diabetes, certain cancers, and several other age-related degenerative disorders. The concept that moderate chocolate consumption could be part of a healthy diet has gained acceptance in past years based on the health benefits ascribed to selected cocoa components. Specifically, cocoa as a plant and chocolate as food contain a series of chemicals that can interact with cell and tissue components, providing protection against the development and amelioration of pathological conditions. The most relevant effects of cocoa and chocolate have been related to cardiovascular disease. The mechanisms behind these effects are still under investigation. However, the maintenance or restoration of vascular NO production and bioavailability and the antioxidant effects are the mechanisms most consistently supported by experimental data. This review will summarize the most recent research on the cardiovascular effects of cocoa flavanols and related compounds.

Original languageEnglish (US)
Pages (from-to)483-490
Number of pages8
JournalJournal of Cardiovascular Pharmacology
Volume54
Issue number6
DOIs
StatePublished - Dec 2009

Fingerprint

Cardiovascular Diseases
Insurance Benefits
Cellular Structures
Vegetables
Biological Availability
Blood Vessels
Fruit
Antioxidants
Maintenance
Diet
Food
Health
Research
Chocolate
Neoplasms
Healthy Diet

Keywords

  • Antioxidant
  • Cardiovascular health
  • Flavanols
  • Flavonoids
  • Hypertension
  • Oxygen radicals

ASJC Scopus subject areas

  • Pharmacology
  • Cardiology and Cardiovascular Medicine

Cite this

Cocoa, chocolate, and cardiovascular disease. / Galleano, Monica; Oteiza, Patricia I.; Fraga, Cesar G.

In: Journal of Cardiovascular Pharmacology, Vol. 54, No. 6, 12.2009, p. 483-490.

Research output: Contribution to journalArticle

Galleano, Monica ; Oteiza, Patricia I. ; Fraga, Cesar G. / Cocoa, chocolate, and cardiovascular disease. In: Journal of Cardiovascular Pharmacology. 2009 ; Vol. 54, No. 6. pp. 483-490.
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