Coastal freshwater runoff is a risk factor for Toxoplasma gondii infection of southern sea otters (Enhydra lutris nereis)

M. A. Miller, Ian Gardner, Christine K Johnson, D. M. Paradies, K. R. Worcester, D. A. Jessup, E. Dodd, M. D. Harris, J. A. Ames, A. E. Packham, Patricia A Conrad

Research output: Contribution to journalArticle

239 Citations (Scopus)

Abstract

The association among anthropogenic environmental disturbance, pathogen pollution and the emergence of infectious diseases in wildlife has been postulated, but not always well supported by epidemiologic data. Specific evidence of coastal contamination of the marine ecosystem with the zoonotic protozoan parasite, Toxoplasma gondii, and extensive infection of southern sea otters (Enhydra lutris nereis) along the California coast was documented by this study. To investigate the extent of exposure and factors contributing to the apparent emergence of T. gondii in southern sea otters, we compiled environmental, demographic and serological data from 223 live and dead sea otters examined between 1997 and 2001. The T. gondii seroprevalence was 42% (49/116) for live otters, and 62% (66/107) for dead otters. Demographic and environmental data were examined for associations with T. gondii seropositivity, with the ultimate goal of identifying spatial clusters and demographic and environmental risk factors for T. gondii infection. Spatial analysis revealed clusters of T. gondii-seropositive sea otters at two locations along the coast, and one site with lower than expected T. gondii seroprevalence. Risk factors that were positively associated with T. gondii seropositivity in logistic regression analysis included male gender, older age and otters sampled from the Morro Bay region of California. Most importantly, otters sampled near areas of maximal freshwater runoff were approximately three times more likely to be seropositive to T. gondii than otters sampled in areas of low flow. No association was found between seropositivity to T. gondii and human population density or exposure to sewage. This study provides evidence implicating land-based surface runoff as a source of T. gondii infection for marine mammals, specifically sea otters, and provides a convincing illustration of pathogen pollution in the marine ecosystem.

Original languageEnglish (US)
Pages (from-to)997-1006
Number of pages10
JournalInternational Journal for Parasitology
Volume32
Issue number8
DOIs
StatePublished - 2002

Fingerprint

Otters
Toxoplasmosis
Fresh Water
Toxoplasma
Seroepidemiologic Studies
Demography
Ecosystem
Spatial Analysis
Zoonoses
Sewage
Population Density
Communicable Diseases
Mammals

Keywords

  • Enhydra lutris
  • Risk factor
  • Runoff
  • Sea otter
  • Spatial analysis
  • Toxoplasma gondii

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Coastal freshwater runoff is a risk factor for Toxoplasma gondii infection of southern sea otters (Enhydra lutris nereis). / Miller, M. A.; Gardner, Ian; Johnson, Christine K; Paradies, D. M.; Worcester, K. R.; Jessup, D. A.; Dodd, E.; Harris, M. D.; Ames, J. A.; Packham, A. E.; Conrad, Patricia A.

In: International Journal for Parasitology, Vol. 32, No. 8, 2002, p. 997-1006.

Research output: Contribution to journalArticle

Miller, M. A. ; Gardner, Ian ; Johnson, Christine K ; Paradies, D. M. ; Worcester, K. R. ; Jessup, D. A. ; Dodd, E. ; Harris, M. D. ; Ames, J. A. ; Packham, A. E. ; Conrad, Patricia A. / Coastal freshwater runoff is a risk factor for Toxoplasma gondii infection of southern sea otters (Enhydra lutris nereis). In: International Journal for Parasitology. 2002 ; Vol. 32, No. 8. pp. 997-1006.
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