CNTRICS final task selection: Long-term memory

John D Ragland, Roshan Cools, Michael Frank, Diego A. Pizzagalli, Alison Preston, Charan Ranganath, Anthony D. Wagner

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Long-term memory (LTM) is a multifactorial construct, composed of different stages of information processing and different cognitive operations that are mediated by distinct neural systems, some of which may be more responsible for the marked memory problems that limit the daily function of individuals with schizophrenia. From the outset of the CNTRICS initiative, this multidimensionality was appreciated, and an effort was made to identify the specific memory constructs and task paradigms that hold the most promise for immediate translational development. During the second CNTRICS meeting, the LTM group identified item encoding and retrieval and relational encoding and retrieval as key constructs. This article describes the process that the LTM group went through in the third and final CNTRICS meeting to select nominated tasks within the 2 LTM constructs and within a reinforcement learning construct that were judged most promising for immediate development. This discussion is followed by each nominating authors' description of their selected task paradigm, ending with some thoughts about future directions.

Original languageEnglish (US)
Pages (from-to)197-212
Number of pages16
JournalSchizophrenia Bulletin
Volume35
Issue number1
DOIs
StatePublished - Jan 2009

Keywords

  • Episodic memory
  • Item memory
  • Relational memory
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Ragland, J. D., Cools, R., Frank, M., Pizzagalli, D. A., Preston, A., Ranganath, C., & Wagner, A. D. (2009). CNTRICS final task selection: Long-term memory. Schizophrenia Bulletin, 35(1), 197-212. https://doi.org/10.1093/schbul/sbn134