CNS relapsed T-cell lymphoma in a young cat

Kyoung Won Seo, Ye In Oh, Sei Myoung Han, Du Min Go, Jeong Ha Lee, Hwa Young Youn

Research output: Contribution to journalArticlepeer-review


An 8-month-old domestic shorthair cat presented with decreased activity and anorexia. Diagnostic imaging revealed cranial mediastinal mass and enlarged mesenteric lymph nodes. Fine needle aspirates showed a marked increase in malignant lymphocytes. Multicentric lymphoma (stage V-b) was diagnosed. The cat treated with COP protocol chemotherapy, and complete remission was induced. CNS relapse developed 314 days after the initiation of chemotherapy. Treatment with rescue protocol greatly reduced the clinical signs for a short period. The cat was in partial remission for 33 days and overall survival time was 383 days. Multicentric T-cell lymphoma with brain involvement was confirmed after necropsy by histopathology and immunohistochemistry.

Original languageEnglish (US)
Pages (from-to)226-232
Number of pages7
JournalJournal of Veterinary Clinics
Issue number3
StatePublished - Jan 1 2014
Externally publishedYes


  • Cat
  • Central nervous system
  • Cytarabine (cytosine arabinoside)
  • Relapsed lymphoma

ASJC Scopus subject areas

  • veterinary(all)


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