Clostridium perfringens–Associated Necrotic Enteritis-Like Disease in Coconut Lorikeets (Trichoglossus haematodus)

Llorenç Grau-Roma, Mauricio Navarro, Sohvi Blatter, Christian Wenker, Sonja Kittl, Francisco A. Uzal, Horst Posthaus

Research output: Contribution to journalArticlepeer-review

Abstract

Several outbreaks of necrotic enteritis-like disease in lorikeets, from which Clostridium perfringens was consistently isolated, are described. All lorikeets had acute, segmental, or multifocal fibrinonecrotizing inflammatory lesions in the small and/or the large intestine, with intralesional gram-positive rods. The gene encoding C. perfringens alpha toxin was detected by PCR (polymerase chain reaction) on formalin-fixed, paraffin-embedded (FFPE) tissues in 20 out of 24 affected lorikeets (83%), but it was not amplified from samples of any of 10 control lorikeets (P <.0001). The second most prevalent C. perfringens toxin gene detected was the beta toxin gene, which was found in FFPE from 7 out of 24 affected lorikeets (29%). The other toxin genes were detected inconsistently and in a relatively low number of samples. These cases seem to be associated with C. perfringens, although the specific type involved could not be determined.

Original languageEnglish (US)
JournalVeterinary pathology
DOIs
StateAccepted/In press - 2020

Keywords

  • alpha toxin
  • beta toxin
  • Clostridium perfringens type A
  • lorikeet
  • necrotizing enteritis
  • NetB toxin
  • Trichoglossus haematodus

ASJC Scopus subject areas

  • veterinary(all)

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