Clostridium perfringens enterotoxin damages the human intestine in vitro

M. E. Fernández Miyakawa, V. Pistone Creydt, Francisco A Uzal, B. A. McClane, C. Ibarra

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Abstract

In vitro, Clostridium perfringens enterotoxin (CPE) binds to human ileal epithelium and induces morphological damage concurrently with reduced short-circuit current, transepithelial resistance, and net water absorption. CPE also binds to the human colon in vitro but causes only slight morphological and transport changes that are not statistically significant

Original languageEnglish (US)
Pages (from-to)8407-8410
Number of pages4
JournalInfection and Immunity
Volume73
Issue number12
DOIs
StatePublished - Dec 2005

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ASJC Scopus subject areas

  • Immunology

Cite this

Fernández Miyakawa, M. E., Pistone Creydt, V., Uzal, F. A., McClane, B. A., & Ibarra, C. (2005). Clostridium perfringens enterotoxin damages the human intestine in vitro. Infection and Immunity, 73(12), 8407-8410. https://doi.org/10.1128/IAI.73.12.8407-8410.2005