Muscle infection with clostridial organisms requires reduced oxygen tensions or a lowered oxidation-reduction potential. A majority of reported equine cases occur as a result of iatrogenic intramuscular injection of nonantibiotic injectables. The pathologic effects of clostridia include the release of various potent exotoxins and enzymes capable of inducing muscle necrosis and systemic inflammation. The disease is rapidly progressive and frequently fatal, requiring a guarded to poor prognosis when diagnosed. Early and aggressive treatment is indicated in suspected cases.
|Original language||English (US)|
|Number of pages||11|
|Journal||Compendium on Continuing Education for the Practicing Veterinarian|
|State||Published - Jun 2001|
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