Clostridial diseases

Francisco A. Uzal, J. Glenn Songer

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations


This chapter provides in-depth coverage of clostridial diseases including relevance, potential public health significance, epidemiology, pathogenesis, clinical signs, lesions, diagnosis, immunity, and prevention and control. Broadly, clostridial diseases of pigs and other animal species are classified into enteric, histotoxic, and neurotoxic infections. Clostridium perfringens type C and C. difficile are well- established enteric pathogens of suckling pigs. The role of C. perfringens type A in enteric disease in pigs is less clear, there being abundant testimonial association with disease but very little experimental evidence supporting C. perfringens type A as a cause of enteric disease in mammals. Neurotoxic clostridial diseases include tetanus caused by C. tetani and botulism caused by T. botulinum. Swine are susceptible to botulism but are in general considered to be among the least susceptible domestic animals. If botulism is suspected, an effort should be made to find the toxin source and prevent further consumption of suspect material by the herd.

Original languageEnglish (US)
Title of host publicationDiseases of Swine
Number of pages15
ISBN (Electronic)9781119350927
ISBN (Print)9781119350859
StatePublished - Mar 29 2019


  • Clostridial diseases
  • Clostridium perfringens
  • Enteric infections
  • Histotoxic infections
  • Neurotoxic infections
  • Pigs

ASJC Scopus subject areas

  • veterinary(all)


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