Clinicopathologic alterations in normal and exhausted endurance horses

Gary P. Carlson, Patrick O. Ocen, Doris Harrold

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Selected clinicopathologic features of normal and exhausted endurance horses were evaluated during conditions of severe heat and work stress. The normal group of horses (Group A) manifested dehydration, hyponatremia, hypokalemia, and hypochloremia. The majority of the horses of Group A had a metabolic alkalosis and a hematologic pattern of response to stress. The data for the group of exhausted horses (Group B) were similar to that for the normal horses, except the majority of the horses of Group B were more severely dehydrated, and plasma potassium values were within the normal range. The acid-base parameters of Group B varied considerably, with the more severely affected horses having a partially compensated respiratory acidosis. Hematologically, horses of Group B had a significant left shift in addition to the stress response. The data are compared with previous reports along with a discussion of the physiologic processes responsible for the alterations observed.

Original languageEnglish (US)
Pages (from-to)93-104
Number of pages12
Issue number2-3
StatePublished - Jan 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


Dive into the research topics of 'Clinicopathologic alterations in normal and exhausted endurance horses'. Together they form a unique fingerprint.

Cite this