Abstract
In order to optimize pediatric traumatic brain injury translational and clinical research, scientific and ethical challenges need to be recognized and addressed. Having recently conducted a multisite phase II safety/feasibility trial of magnesium sulfate as a neuroprotective agent, we supplement our own experience by a mini review of similar studies, identifying challenges and possible responses from the perspective of families, investigators, funding agencies and society.
Original language | English (US) |
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Pages (from-to) | 276-290 |
Number of pages | 15 |
Journal | Developmental Neuroscience |
Volume | 28 |
Issue number | 4-5 |
DOIs | |
State | Published - Aug 2006 |
Keywords
- Patient recruitment
- Pediatric traumatic brain injury
- Translational research
ASJC Scopus subject areas
- Neuroscience(all)