Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer

Bevin Lin, Shiro Urayama, Ramez M G Saroufeem, Dennis L Matthews, Stavros G. Demos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The non-invasiveness of autofluorescence technology may reduce sampling error and time delay for histopathology diagnosis. We establish biophotonic methods and guidelines to visualize and interpret early epithelial tissue changes that signify disease. Flexible and rigid fiber endomicroscopy instrumentation design parameters feasible for translation towards clinical use are in development.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Volume7990
DOIs
StatePublished - 2011
EventOptical Sensors and Biophotonics II - Shanghai, China
Duration: Dec 8 2010Dec 12 2010

Other

OtherOptical Sensors and Biophotonics II
CountryChina
CityShanghai
Period12/8/1012/12/10

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Keywords

  • Autofluorescence
  • Endoscopy
  • Gastrointestinal
  • Microscopy
  • Real-time diagnostic imaging

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Lin, B., Urayama, S., Saroufeem, R. M. G., Matthews, D. L., & Demos, S. G. (2011). Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 7990). [799002] https://doi.org/10.1117/12.888682