Clinical Pharmacology and Administration of Fluid, Electrolyte, and Blood Component Solutions

Amandeep Chohan, Elizabeth B. Davidow

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations


The body fluids can be thought of as existing in two major compartments: intracellular (ICF) and extracellular (ECF) fluid compartments in order to understand distribution of body water. Fluid shifts between intravascular (IVF; plasma) and interstitial (ISF) fluid compartments occur at the level of capillaries. Crystalloid solutions are prepared by dissolving crystalline compounds in water. Colloids are composed of macromolecular particles suspended in a crystalloid fluid solution. The objective of perioperative fluid therapy is to maintain circulatory volume so that end-organ perfusion and oxygen delivery are not compromised. Sodium is the most abundant cation in the ECF. There are limited publications in the veterinary literature specifically about use of transfusions in the perioperative period and during anesthesia. Red blood cell (RBC) products are indicated in anemic patients to improve their oxygen-carrying capacity. Transfusion reactions are categorized as immune mediated or nonimmunologic as well as acute or chronic.

Original languageEnglish (US)
Title of host publicationVeterinary Anesthesia and Analgesia
Subtitle of host publicationThe Fifth Edition of Lumb and Jones
Number of pages28
ISBN (Electronic)9781119421375
ISBN (Print)9781118526231
StatePublished - Apr 28 2017
Externally publishedYes


  • Blood component therapy
  • Body fluids
  • Crystalloid fluid solution
  • Extracellular fluid compartments
  • Intracellular fluid compartments
  • Intravascular fluid compartments
  • Perioperative fluid therapy
  • Sodium
  • Synthetic colloids
  • Transfusion reactions

ASJC Scopus subject areas

  • veterinary(all)


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