Clinical outcome of nonnasal chondrosarcoma in dogs

Thirty-one cases (1986-2003)

Suzanne Shelly Waltman, Bernard Seguin, Barry J. Cooper, Michael S Kent

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objective To evaluate metastatic rate and survival times of dogs with chondrosarcoma of nonnasal bony sites treated by wide surgical excision. Study Design Retrospective study. Animals Dogs (n=31) with chondrosarcoma. Methods Medical records were retrospectively reviewed to identify dogs with chondrosarcoma of bone in potentially surgically accessible sites. When complete information was not available in the medical record, owners and referring veterinarians were contacted by telephone to evaluate the course of disease and survival times. When possible, histopathologic diagnosis was confirmed by a single board certified pathologist and tumors were histologically graded. Results Dogs treated by wide surgical excision (n=18) had a mean survival time of 3097 days and did not reach median survival time. Dogs untreated except for diagnostic biopsy (n =13) had a median survival time of 523 days and a mean survival time of 495 days. Method of treatment and tumor grade predicted survival time (P=.016 and P=.007, respectively). Metastatic rate was 28% for treated dogs and 15% for untreated dogs, with no significant difference between the 2 groups (P=.39). Conclusions Wide surgical excision significantly improves survival time for dogs with chondrosarcoma of nonnasal bony sites, but does not affect the likelihood of metastasis. Grade may be prognostic for survival. Clinical Relevance Surgical excision benefits dogs with chondrosarcoma and can result in prolonged survival times. Metastasis still occurs in ∼1 of 4 dogs even after surgical resection.

Original languageEnglish (US)
Pages (from-to)266-271
Number of pages6
JournalVeterinary Surgery
Volume36
Issue number3
DOIs
StatePublished - Apr 2007

Fingerprint

Chondrosarcoma
Dogs
dogs
excision
metastasis
Medical Records
Neoplasm Metastasis
neoplasms
Veterinarians
resection
retrospective studies
Telephone
disease course
veterinarians
biopsy
Neoplasms
Retrospective Studies
experimental design
bones
Biopsy

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Clinical outcome of nonnasal chondrosarcoma in dogs : Thirty-one cases (1986-2003). / Waltman, Suzanne Shelly; Seguin, Bernard; Cooper, Barry J.; Kent, Michael S.

In: Veterinary Surgery, Vol. 36, No. 3, 04.2007, p. 266-271.

Research output: Contribution to journalArticle

Waltman, Suzanne Shelly ; Seguin, Bernard ; Cooper, Barry J. ; Kent, Michael S. / Clinical outcome of nonnasal chondrosarcoma in dogs : Thirty-one cases (1986-2003). In: Veterinary Surgery. 2007 ; Vol. 36, No. 3. pp. 266-271.
@article{513ec48e32b64f078515e39b4b2e0161,
title = "Clinical outcome of nonnasal chondrosarcoma in dogs: Thirty-one cases (1986-2003)",
abstract = "Objective To evaluate metastatic rate and survival times of dogs with chondrosarcoma of nonnasal bony sites treated by wide surgical excision. Study Design Retrospective study. Animals Dogs (n=31) with chondrosarcoma. Methods Medical records were retrospectively reviewed to identify dogs with chondrosarcoma of bone in potentially surgically accessible sites. When complete information was not available in the medical record, owners and referring veterinarians were contacted by telephone to evaluate the course of disease and survival times. When possible, histopathologic diagnosis was confirmed by a single board certified pathologist and tumors were histologically graded. Results Dogs treated by wide surgical excision (n=18) had a mean survival time of 3097 days and did not reach median survival time. Dogs untreated except for diagnostic biopsy (n =13) had a median survival time of 523 days and a mean survival time of 495 days. Method of treatment and tumor grade predicted survival time (P=.016 and P=.007, respectively). Metastatic rate was 28{\%} for treated dogs and 15{\%} for untreated dogs, with no significant difference between the 2 groups (P=.39). Conclusions Wide surgical excision significantly improves survival time for dogs with chondrosarcoma of nonnasal bony sites, but does not affect the likelihood of metastasis. Grade may be prognostic for survival. Clinical Relevance Surgical excision benefits dogs with chondrosarcoma and can result in prolonged survival times. Metastasis still occurs in ∼1 of 4 dogs even after surgical resection.",
author = "Waltman, {Suzanne Shelly} and Bernard Seguin and Cooper, {Barry J.} and Kent, {Michael S}",
year = "2007",
month = "4",
doi = "10.1111/j.1532-950X.2007.00261.x",
language = "English (US)",
volume = "36",
pages = "266--271",
journal = "Veterinary Surgery",
issn = "0161-3499",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Clinical outcome of nonnasal chondrosarcoma in dogs

T2 - Thirty-one cases (1986-2003)

AU - Waltman, Suzanne Shelly

AU - Seguin, Bernard

AU - Cooper, Barry J.

AU - Kent, Michael S

PY - 2007/4

Y1 - 2007/4

N2 - Objective To evaluate metastatic rate and survival times of dogs with chondrosarcoma of nonnasal bony sites treated by wide surgical excision. Study Design Retrospective study. Animals Dogs (n=31) with chondrosarcoma. Methods Medical records were retrospectively reviewed to identify dogs with chondrosarcoma of bone in potentially surgically accessible sites. When complete information was not available in the medical record, owners and referring veterinarians were contacted by telephone to evaluate the course of disease and survival times. When possible, histopathologic diagnosis was confirmed by a single board certified pathologist and tumors were histologically graded. Results Dogs treated by wide surgical excision (n=18) had a mean survival time of 3097 days and did not reach median survival time. Dogs untreated except for diagnostic biopsy (n =13) had a median survival time of 523 days and a mean survival time of 495 days. Method of treatment and tumor grade predicted survival time (P=.016 and P=.007, respectively). Metastatic rate was 28% for treated dogs and 15% for untreated dogs, with no significant difference between the 2 groups (P=.39). Conclusions Wide surgical excision significantly improves survival time for dogs with chondrosarcoma of nonnasal bony sites, but does not affect the likelihood of metastasis. Grade may be prognostic for survival. Clinical Relevance Surgical excision benefits dogs with chondrosarcoma and can result in prolonged survival times. Metastasis still occurs in ∼1 of 4 dogs even after surgical resection.

AB - Objective To evaluate metastatic rate and survival times of dogs with chondrosarcoma of nonnasal bony sites treated by wide surgical excision. Study Design Retrospective study. Animals Dogs (n=31) with chondrosarcoma. Methods Medical records were retrospectively reviewed to identify dogs with chondrosarcoma of bone in potentially surgically accessible sites. When complete information was not available in the medical record, owners and referring veterinarians were contacted by telephone to evaluate the course of disease and survival times. When possible, histopathologic diagnosis was confirmed by a single board certified pathologist and tumors were histologically graded. Results Dogs treated by wide surgical excision (n=18) had a mean survival time of 3097 days and did not reach median survival time. Dogs untreated except for diagnostic biopsy (n =13) had a median survival time of 523 days and a mean survival time of 495 days. Method of treatment and tumor grade predicted survival time (P=.016 and P=.007, respectively). Metastatic rate was 28% for treated dogs and 15% for untreated dogs, with no significant difference between the 2 groups (P=.39). Conclusions Wide surgical excision significantly improves survival time for dogs with chondrosarcoma of nonnasal bony sites, but does not affect the likelihood of metastasis. Grade may be prognostic for survival. Clinical Relevance Surgical excision benefits dogs with chondrosarcoma and can result in prolonged survival times. Metastasis still occurs in ∼1 of 4 dogs even after surgical resection.

UR - http://www.scopus.com/inward/record.url?scp=34247402148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247402148&partnerID=8YFLogxK

U2 - 10.1111/j.1532-950X.2007.00261.x

DO - 10.1111/j.1532-950X.2007.00261.x

M3 - Article

VL - 36

SP - 266

EP - 271

JO - Veterinary Surgery

JF - Veterinary Surgery

SN - 0161-3499

IS - 3

ER -