Clinical management of suspected intracranial meningioma in three dogs with pulsed high-dose hydroxyurea

Jae Geum Cho, Kun Ho Song, Kyoung Won Seo

Research output: Contribution to journalArticle

Abstract

Three aged dogs, all over 15 years old, with multiple seizure events and various neurologic signs such as head turn and ataxia were brought to the referring hospital. Two cases were tentatively diagnosed with intracranial meningioma based on magnetic resonance imaging, and one case was histopathologically confirmed as meningioma at necropsy. All dogs improved after initiation of pulsed high-dose hydroxyurea (HU) treatment. Clinical sign relapses were managed by repeating high-dose HU without obvious side effects. Pulsed high-dose HU can be applied when clinical signs are refractory to the traditionally recommended dosage for intracranial meningioma in dogs.

Original languageEnglish (US)
Pages (from-to)103-106
Number of pages4
JournalKorean Journal of Veterinary Research
Volume58
Issue number2
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

Fingerprint

hydroxyurea
Hydroxyurea
Meningioma
Dogs
dogs
dosage
Ataxia
Neurologic Manifestations
relapse
Seizures
seizures
Head
magnetic resonance imaging
Magnetic Resonance Imaging
nervous system
Recurrence
necropsy
adverse effects

Keywords

  • Brain neoplasms
  • Chemotherapy
  • Hydroxyurea
  • Meningioma
  • Seizures

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Clinical management of suspected intracranial meningioma in three dogs with pulsed high-dose hydroxyurea. / Cho, Jae Geum; Song, Kun Ho; Seo, Kyoung Won.

In: Korean Journal of Veterinary Research, Vol. 58, No. 2, 01.01.2018, p. 103-106.

Research output: Contribution to journalArticle

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