Clinical features of Behçets disease: A retrospective chart review of 26 patients

Parastoo Davari, Roy S. Rogers, Brian Chan, Travis H. Nagler, Nasim Fazel

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: Behçets disease (BD) is a multi-organ inflammatory disorder with mucocutaneous, ocular, neurological, musculoskeletal, gastrointestinal, and pulmonary manifestations. The aim of this study was to determine the clinical features of BD in a cohort of patients diagnosed at the University of California, Davis, United States. Methods: The medical records of 59 patients with an ICD9-code of BD were retrospectively reviewed. The International Criteria for BD was used to identify patients with a point score ≥5. The clinical manifestations of BD were investigated over a 10-year period in this cohort. Results: Twenty-six patients (20 women, six men; female:male ratio = 3.3:1.0) had a point score ≥5 based on the International Criteria. The average age of onset of BD was 29.25 ± 14.25 years. Oral ulcers (100%), genital ulcers (84.6%), articular involvement (69.2%), ocular involvement (65.3%), and skin lesions (50.0%) were the most prevalent manifestations of BD in this cohort. Conclusion: Oral ulcers were the most common presenting and lifetime sign of BD. In our cohort, oral and genital ulcers were hallmarks of BD, independent of patient demographics. Thus, patients with these signs require close surveillance for other manifestations of the disease.

Original languageEnglish (US)
Pages (from-to)70-74
Number of pages5
JournalJournal of Dermatological Treatment
Volume27
Issue number1
DOIs
StatePublished - Jan 2 2016

Keywords

  • Aphthosis
  • Behcet's disease
  • erythema nodosum
  • genital ulcer
  • oral ulcer
  • uveitis

ASJC Scopus subject areas

  • Dermatology

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