Clinical features in 9 dogs with immune-mediated polyarthritis

Seula Lim, Kun Ho Song, Kyoung Won Seo

Research output: Contribution to journalArticlepeer-review


Nine dogs with history of lameness and anorexia were presented. On physical examination, all dogs had gait abnormality and six dogs had high body temperature. Their clinical signs were mostly episodic, and only non-specific symptoms were occasionally observed. Arthrocentesis was performed in all dogs, and immune-mediated polyarthritis (IMPA) was diagnosed. Definitive rheumatoid arthritis (RA) and systemic lupus erythematous (SLE) were diagnosed in one dogs, one each. Prednisolone (PDS) was chosen as the first-line therapy for all dogs, except for the one with RA. Most cases responded to PDS but some cases including those of SLE and RA were refractory to PDS. IMPA can be challenging to diagnose due to its vague symptom and is commonly implicated in ‘fever of unknown origin’. Therefore, clinicians should consider IMPA as a differential diagnosis when the patient has fever with systemic, non-specific signs, such as anorexia and depression, but does not respond to antibiotics.

Original languageEnglish (US)
Pages (from-to)434-436
Number of pages3
JournalJournal of Veterinary Clinics
Issue number6
StatePublished - Dec 1 2017
Externally publishedYes


  • Arthrocentesis
  • Fever
  • Immune mediated polyarthritis
  • Lameness

ASJC Scopus subject areas

  • veterinary(all)


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