Clinical Aspects of Alzheimer's Disease in Black and White Patients

Rita Hargrave, Maria Stoeklin, Mary Haan, Bruce R Reed

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

This article examines the association between ethnicity and psychiatric symptoms in patients with Alzheimer's disease. Data from a cross-sectional study of patients evaluated at nine California Department of Health Alzheimer's Disease Diagnostic and Treatment Centers (ADDTCs) were used. Using the ADDTC patient database, sociodemographic and clinical variables in 207 black patients and 1818 white patients with probable and possible Alzheimer's disease were compared. Logistic and linear regression analysis indicated the following results: 1) black patients had fewer years of education and more often had hypertension, 2) black patients reported shorter duration of illness at the time of initial diagnosis of dementia, 3) black patients had lower Mini-Mental State Examination scores and higher Blessed Roth Dementia Rating Scale scores at the time of initial diagnosis, and 4) black patients more frequently reported insomnia and less frequently reported anxiety. Additional studies are needed to validate these findings and to generate hypotheses about the role of cardiovascular disease and pathophysiology of psychiatric symptoms in ethnic populations with Alzheimer's disease.

Original languageEnglish (US)
Pages (from-to)78-84
Number of pages7
JournalJournal of the National Medical Association
Volume90
Issue number2
StatePublished - Feb 1998

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Alzheimer Disease
Psychiatry
Dementia
hydroquinone
Sleep Initiation and Maintenance Disorders
Linear Models
Cardiovascular Diseases
Anxiety
Cross-Sectional Studies
Logistic Models
Regression Analysis
Databases
Hypertension
Education
Health
Therapeutics
Population

Keywords

  • Alzheimer's disease
  • Race

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Clinical Aspects of Alzheimer's Disease in Black and White Patients. / Hargrave, Rita; Stoeklin, Maria; Haan, Mary; Reed, Bruce R.

In: Journal of the National Medical Association, Vol. 90, No. 2, 02.1998, p. 78-84.

Research output: Contribution to journalArticle

Hargrave, Rita ; Stoeklin, Maria ; Haan, Mary ; Reed, Bruce R. / Clinical Aspects of Alzheimer's Disease in Black and White Patients. In: Journal of the National Medical Association. 1998 ; Vol. 90, No. 2. pp. 78-84.
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