Clear Liquids versus Polyethylene Glycol Preparation for Video Capsule Endoscopy of the Small Bowel: A Randomized Controlled Trial

Runalia Bahar, Asha Gupta, Surinder K Mann

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Background: An effective bowel cleanse can improve the imaging quality of video capsule endoscopy (VCE). We aimed to further investigate the optimal small bowel cleanse method by comparing the efficacy of 4 L of clear liquids, 2 L of polyethylene glycol (PEG), and 4 L of PEG on the image quality of VCE. Methods: A randomized controlled, non-inferiority trial was performed comparing 4 L of clear liquids (Group A), 2 L of PEG (Group B), and 4 L of PEG (Group C). The primary endpoint was image quality between the groups. The secondary endpoints included patient tolerability and side effects. Results: Eighty-one patients were analyzed in group A, 84 patients were analyzed in group B, and 80 patients were analyzed in group C. Image quality scores revealed 4 L of clear liquids to be non-inferior to 2 L of PEG, and 2 L of PEG to be non-inferior to 4 L of PEG (p < 0.0167). Group A had a lower difficulty of completion rate than Group B and Group C and a lower rate of side effects when compared to Group C (p < 0.0167). Conclusion: Four liters of clear liquids should be considered a routine method for small bowel preparation prior to VCE.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalDigestion
DOIs
StateAccepted/In press - Jan 1 2018

Keywords

  • Image quality
  • Preparation
  • Small Bowel
  • Video capsule endoscopy

ASJC Scopus subject areas

  • Gastroenterology

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