Classification of adverse reproductive effects can be improved by measurements of multiple biomarkers for ovarian toxicity and early fetal loss

B. L. Lasley, Ellen B Gold, S. T. Nakajima, D. R. Stewart, J. W. Overstreet

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Hormone assays have been developed and applied for monitoring reproductive function using self-collected urine samples in non-clinical populations of women. Early pregnancy loss, menstrual dysfunction, reduced fertility as well as the site of toxicity can now be assessed using daily early morning urine samples. The understanding of the specific limitations of individual assay systems is important, however, to make the best use of these systems. The use of multiple end-points and computer algorithms is suggested to avoid misclassification of adverse reproductive events.

Original languageEnglish (US)
Pages (from-to)423-433
Number of pages11
JournalJournal of Toxicology and Environmental Health
Volume40
Issue number2-3
StatePublished - 1993

ASJC Scopus subject areas

  • Toxicology
  • Pollution

Fingerprint Dive into the research topics of 'Classification of adverse reproductive effects can be improved by measurements of multiple biomarkers for ovarian toxicity and early fetal loss'. Together they form a unique fingerprint.

  • Cite this