Circulatory effects of halothane and halothane nitrous oxide anesthesia in the dog: spontaneous ventilation

Eugene Steffey, J. R. Gillespie, J. D. Berry, E. I. Eger, E. A. Rhode

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The cardiovascular effects of equipoxent (minimum alveolar concentration) doses of halothane versus halothane plus 25% N 2O (H25N 2O) in spontaneously breathing dogs do not differ except that nitrous oxide increased mean arterial pressure (AP) and decreased arterial oxygen partial pressure (Pao 2). When 75% nitrous oxide was added to halothane anesthesia, AP, mean pulmonary artery pressure, heart rate, cardiac output, stroke volume, total peripheral resistance and left ventricular work increased and Pao 2 and hemoglobin saturation decreased. Arterial oxygen tensions below 80 torr were common at moderate and deep anesthetic levels of halothane plus 75% N 2O (H75N 2O). The specific contribution of N 2O, hypoxemia, hypercapnia, or temporal recovery (or a combination of these) in producing cardiovascular stimulation were not determined.

Original languageEnglish (US)
Pages (from-to)197-200
Number of pages4
JournalAmerican Journal of Veterinary Research
Volume36
Issue number2
StatePublished - Jan 1 1975

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Nitrous Oxide
halothane
Halothane
nitrous oxide
Ventilation
anesthesia
Anesthesia
Dogs
Arterial Pressure
dogs
Oxygen
oxygen
hypercapnia
Hypercapnia
pulmonary artery
Partial Pressure
cardiac output
stroke
anesthetics
Cardiac Output

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Circulatory effects of halothane and halothane nitrous oxide anesthesia in the dog : spontaneous ventilation. / Steffey, Eugene; Gillespie, J. R.; Berry, J. D.; Eger, E. I.; Rhode, E. A.

In: American Journal of Veterinary Research, Vol. 36, No. 2, 01.01.1975, p. 197-200.

Research output: Contribution to journalArticle

Steffey, Eugene ; Gillespie, J. R. ; Berry, J. D. ; Eger, E. I. ; Rhode, E. A. / Circulatory effects of halothane and halothane nitrous oxide anesthesia in the dog : spontaneous ventilation. In: American Journal of Veterinary Research. 1975 ; Vol. 36, No. 2. pp. 197-200.
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