Ciprofloxacin-Induced Tendinopathy of the Gluteal Tendons

Kaumakaokalani Shimatsu, Somasundaram Subramaniam, Helen Sim, Paul B Aronowitz

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Fluoroquinolone-induced tendinopathy most commonly affects the Achilles tendon; however, involvement of several other tendons has been described. This is a case report of ciprofloxacin-induced tendinopathy of the gluteal tendons with MRI findings. An obese 25-year-old woman with no significant past medical history was diagnosed with acute pyelonephritis and was treated with intravenous ciprofloxacin. Shortly after her first dose of ciprofloxacin, she developed severe left hip pain and decreased range of motion. MRI of the hips showed bilateral tendinopathy of the gluteal muscle insertion. A diagnosis of ciprofloxacin-induced tendinopathy was made based on her MRI and a Naranjo score of 7. Ciprofloxacin was stopped and her pain quickly resolved. Fluoroquinolones cause tendinopathy in 0.14 % to 0.4 % of patients using these agents. Fluoroquinolone-associated tendinopathy is a serious adverse reaction that can affect many tendons and should be considered in any patient presenting with new musculoskeletal complaints and in whom there is a history of fluoroquinolone use within the preceding 6 months.

Original languageEnglish (US)
Pages (from-to)1559-1562
Number of pages4
JournalJournal of General Internal Medicine
Issue number11
StatePublished - 2014


  • ciprofloxacin
  • fluoroquinolone
  • gluteal
  • tendinopathy
  • tendon

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)


Dive into the research topics of 'Ciprofloxacin-Induced Tendinopathy of the Gluteal Tendons'. Together they form a unique fingerprint.

Cite this