cIAP Proteins: Keystones in NOD Receptor Signal Transduction

Colin Reardon, Tak W. Mak

Research output: Contribution to journalShort survey

9 Scopus citations

Abstract

NOD1 and 2 are intracellular sentinels critical to innate immunity. In this issue of Immunity, Bertrand et al. (2009) fill in a gap in the NOD signaling cascade by demonstrating that cIAP1 and 2 function as E3 ubiquitin ligases for the RIP2 signaling molecule.

Original languageEnglish (US)
Pages (from-to)755-756
Number of pages2
JournalImmunity
Volume30
Issue number6
DOIs
StatePublished - Jun 19 2009
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases
  • Immunology

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