Chronic cholinesterase inhibition does not modify amygdaloid kindling

Robert M. Joy, Larry G. Stark, Linda S. Gordon, Steven L. Peterson, Timothy E Albertson

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The consequences of chronic cholinesterase inhibition during kindling were examined to further evaluate the importance of cholinergic function in kindling development and maintenance. Inhibition of brain and serum cholinesterases of as much as 80% were produced by the daily administration of 0.5 or 2.0 mg/kg parathion. The degrees in inhibition attained had no significant effects upon the rate or expression of kindling.

Original languageEnglish (US)
Pages (from-to)588-594
Number of pages7
JournalExperimental Neurology
Volume73
Issue number2
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neurology

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