Chronic cholinesterase inhibition does not modify amygdaloid kindling

Robert M. Joy; Larry G. Stark; Linda S. Gordon; Steven L. Peterson; Timothy E Albertson

doi:10.1016/0014-4886(81)90293-4

Chronic cholinesterase inhibition does not modify amygdaloid kindling

Robert M. Joy, Larry G. Stark, Linda S. Gordon, Steven L. Peterson, Timothy E Albertson

Pulmonary, Critical Care, and Sleep Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The consequences of chronic cholinesterase inhibition during kindling were examined to further evaluate the importance of cholinergic function in kindling development and maintenance. Inhibition of brain and serum cholinesterases of as much as 80% were produced by the daily administration of 0.5 or 2.0 mg/kg parathion. The degrees in inhibition attained had no significant effects upon the rate or expression of kindling.

Original language	English (US)
Pages (from-to)	588-594
Number of pages	7
Journal	Experimental Neurology
Volume	73
Issue number	2
DOIs	https://doi.org/10.1016/0014-4886(81)90293-4
State	Published - 1981

ASJC Scopus subject areas

Neuroscience(all)
Neurology

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title = "Chronic cholinesterase inhibition does not modify amygdaloid kindling",

abstract = "The consequences of chronic cholinesterase inhibition during kindling were examined to further evaluate the importance of cholinergic function in kindling development and maintenance. Inhibition of brain and serum cholinesterases of as much as 80% were produced by the daily administration of 0.5 or 2.0 mg/kg parathion. The degrees in inhibition attained had no significant effects upon the rate or expression of kindling.",

author = "Joy, {Robert M.} and Stark, {Larry G.} and Gordon, {Linda S.} and Peterson, {Steven L.} and Albertson, {Timothy E}",

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AB - The consequences of chronic cholinesterase inhibition during kindling were examined to further evaluate the importance of cholinergic function in kindling development and maintenance. Inhibition of brain and serum cholinesterases of as much as 80% were produced by the daily administration of 0.5 or 2.0 mg/kg parathion. The degrees in inhibition attained had no significant effects upon the rate or expression of kindling.

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