Chronic ambient hydrogen sulfide exposure and cognitive function

Bruce R Reed, Julian Crane, Nick Garrett, David L Woods, Michael N. Bates

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Background: Exposures to hydrogen sulfide gas (H2S) have been inconclusively linked to a variety of negative cognitive outcomes. We investigated possible effects on cognitive function in an urban population with chronic, low-level exposure to H2S. Methods: Participants were 1637 adults, aged 18-65years from Rotorua city, New Zealand, exposed to ambient H2S from geothermal sources. Exposures at homes and workplaces were estimated from data collected by summer and winter H2S monitoring networks across Rotorua in 2010/11. Metrics for H2S exposure at the time of participation and for exposure over the last 30years were calculated. H2S exposure was modeled both as continuous variables and as quartiles of exposure covering the range of 0-64ppb (0-88μg/m3). Outcomes were neuropsychological tests measuring visual and verbal episodic memory, attention, fine motor skills, psychomotor speed and mood. Associations between cognition and measures of H2S exposure were investigated with multiple regression, while covarying demographics and factors known to be associated with cognitive performance. Results: The consistent finding was of no association between H2S exposure and cognition. Quartiles of H2S exposure had a small association with simple reaction time: higher exposures were associated with faster response times. Similarly, for digit symbol, higher H2S exposures tended to be marginally associated with better performance. Conclusion: The results provide evidence that chronic H2S exposure, at the ambient levels found in and around Rotorua, is not associated with impairment of cognitive function.

Original languageEnglish (US)
Pages (from-to)68-76
Number of pages9
JournalNeurotoxicology and Teratology
Volume42
DOIs
StatePublished - 2014

Fingerprint

Hydrogen Sulfide
Cognition
Reaction Time
Gases
Data storage equipment
Motor Skills
Urban Population
Episodic Memory
Monitoring
Neuropsychological Tests
New Zealand
Workplace
Demography

Keywords

  • Cognitive function
  • Cross-sectional study
  • Geothermal
  • Hydrogen sulfide
  • Neuropsychological tests
  • New Zealand

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Cellular and Molecular Neuroscience
  • Toxicology
  • Medicine(all)

Cite this

Chronic ambient hydrogen sulfide exposure and cognitive function. / Reed, Bruce R; Crane, Julian; Garrett, Nick; Woods, David L; Bates, Michael N.

In: Neurotoxicology and Teratology, Vol. 42, 2014, p. 68-76.

Research output: Contribution to journalArticle

Reed, Bruce R ; Crane, Julian ; Garrett, Nick ; Woods, David L ; Bates, Michael N. / Chronic ambient hydrogen sulfide exposure and cognitive function. In: Neurotoxicology and Teratology. 2014 ; Vol. 42. pp. 68-76.
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