Chronic administration of ketamine for analgesia

Alon Ben-Ari, Michael C. Lewis, Elyad Davidson

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Use of the dissociative anesthetic ketamine in subanesthetic doses has demonstrated efficacy in neuropathic pain. This article reviews the scientific and clinical literature on ketamine. Mechanisms of both central and peripheral neuropathic pain are described. Studies of ketamine analgesia in postherpetic neuralgia, phantom pain, complex regional pain syndrome and cancer pain are reviewed. A range of administration methods for ketamine including neuroaxial administration are described.

Original languageEnglish (US)
Pages (from-to)7-14
Number of pages8
JournalJournal of Pain and Palliative Care Pharmacotherapy
Issue number1
StatePublished - Mar 19 2007
Externally publishedYes


  • Cancer
  • Efficacy
  • Ketamine
  • Neuroaxial
  • Neuropathic
  • Pain
  • Phantom
  • Postherpetic neuralgia
  • Safety
  • Topical

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Anesthesiology and Pain Medicine
  • Pharmacology (medical)


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